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hey #teamtomo if you are looking to add to your toolkit for molecular identification inside cells, our preprint is now out!

I have written a concise review on chromatin transcription as part of the Journal of Molecular Biology special issue on transcription elongation. Check it out! authors.elsevier.com/sd/article/S00…

最も尊敬する女性研究者の訃報。。私がモデル植物シロイヌナズナの発生遺伝学者を志すきっかけであり、ロールモデルでもある憧れの偉大な研究者。RIP, Joanne, you are my hero and the reason why I became a plant developmental biologist...🌱

This week's lesson: You never know until you try. You might discover a hidden talent. (DH5a sometimes provides the best protein expression🙃)

Excited that our work on transcription-coupled DNA repair is now published Cell! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples stalled Pol II to TFIIH. 🧬🐸 ➡️ cell.com/cell/fulltext/…

Like astronauts exploring a planet, no stone is left unturned in the Giunta Lab when it comes to human DNA 🧬Our computational simulations show that centromere sequences are intrinsically prone to complex and unstable secondary structures correlated with chromosome missegregation

Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date). John Innes Centre DurhamUniversity Malopolska Centre of Biotechnology UJ

Ever wondered how transcription choreographs histone modifications? Our work reveals the basis of co-transcriptional H3K36me3 by SETD2. We visualize how a histone writer coordinates with the transcription machinery! This is the magnus opus of Jon Markert tinyurl.com/setd2

Checkout our transcription-coupled histone methylation deposition story! Structural biology of chromatin transcription finally approaches histone modification!!!

1/ Thrilled to announce Dr. Elizabeth Wright from UW–Madison Biochem as the inaugural winner of the June Almeida Award for #cryoem! 🎉Elizabeth’s pioneering work in both cryo-ET methods and structural virology made her a perfect fit for this award. Congrats, Elizabeth Wright! ❄️🔬

Check out a fantastic eLife - the journal article highlighting Yasuhiro Arimura’s MagIC #cryoEM technique - a method using specialized magnetic beads that makes it possible to study the structure of proteins from dilute samples. elifesciences.org/articles/105335

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Our new paper about the cryo-EM structures of barrier-to-autointegration factor (BAF) and Lamin A/C complexed with nucleosomes has been published! This study reveals that BAF and Lamin A/C interact with nucleosomes in multiple binding modes. rdcu.be/d9jmd

Congrats to Fred Hutch evolutionary biologist Bloom Lab on being named a fellow of the American Academy of Microbiology, a prestigious leadership group within ASM! Read more: bit.ly/3EFmnb1

Super excited to share our work on the chromatin-associated oncoprotein DEK published in NatureStructMolBiol!!😆 We found DEK as a nucleosome binding protein that facilitates H3K27me3 by PRC2 through chromatin reorganization!! Check out! rdcu.be/eaSK6

Excited to share our pre-print on the molecular architecture of heterochromatin in human cells🧬🔬 w/ Jan Philipp Kreysing, Johannes Betz,Turoňová lab, Marina Lusic, Hummer lab, Beck Laboratory, Max Planck Institute of Biophysics 🔗 Preprint here: doi.org/10.1101/2025.0…

Wow. So nice😳 I am speechless.

My lab is hiring a research assistant to work on 3D genome architecture in frog embryos. Please spread the word! #xenopus #chromatin 🐸 🧬🔬 employment.ku.edu/jobs/staff/ass…

We’re hiring two research administrators! Join us and help support the innovative and exciting research happening in the Basic Sciences Division @FredHutch. Learn more and apply: fredhutch.org/en/research/di…