Thanks L. Felipe Benites for the interest in my talk at #AbSciCon22 #AbSciCon2022. In this talk I discussed my research at SijbrenOttoLab on how the integration of life's main characteristics in one single system can bring us one step closer to de-novo life.

SijbrenOttoLab #AbSciCon2022 #AbSciCon22

SijbrenOttoLab's latest manuscript is now available on ChemRxiv. The manuscript describes how complex ecological-evolutionary dynamics can be realized in a synthetic replicator system. chemrxiv.org/engage/chemrxi… #systemschemistry

Read out my interview with Trouw about de novo life and my research at SijbrenOttoLab on compartmentalization as one of the pillars of life: Gronings lab maakt leven uit niets: ‘De moluculen in onze systemen vind je niet in een levende cel’ trouw.nl/ts-bef77ea8 via Trouw

Mooi bericht uit het SijbrenOttoLab: Dit Groningse lab maakt leven uit niets: ‘Deze moleculen vind je niet in een levende cel’ trouw.nl/ts-bef77ea8 via Trouw Over experimenten waarin nieuw leven zou kunnen ontstaan.

We have a job opening for a PhD position on 'Understanding Symbiosis between Synthetic Cells', and look forward to welcoming a new member to our team! Please retweet / share if you know someone who might be interested! #coacervates #liposomes #protocells ru.nl/en/working-at/…

The YAG is deeply concerned about reports from Sharif University in Teheran where forces trapped and attacked protesters. We stand in solidarity with students and academics there and elsewhere.

Check our our latest preprint 👇- Shuo & Yannick have done some amazing work on chiral selective replicators & why they happen to be so. Includes one that grows from racemic food but incorporates only its own enantiomer! doi.org/10.26434/chemr…

Homochirality is a signature of life, but the origin of that is unclear. Check out our new paper published J. Am. Chem. Soc. in which we showed how chiral amplification can be achieved by chiral selective self-replicators. Congrats to Shuo Yang and Yannick Geiger | @yannickgeiger.bsky.social and other authors

Super stocked for being a part of a work just published Nature Chemistry in which we showed Darwinian evolution outside biology in a system of synthetic self-replicators & arising behaviour analogous to eco-evolutionary dynamics in it. Congrats to SijbrenOttoLab, Kai Liu & all authors.

Reminder 📢 We have a total of three PhS positions open! Two within a MSCA ITN, more at darchem-dn.eu. Applicants should have been no longer than 12 months in NL ober the last 3 years; deadline 31 oct. One more position on diff. funding is without residence constraints.

BREAKING💥Ottogroup was awarded an ERC synergy grant, together with Gonen Ashkenasy and the groups of Eörs Szathmáry and Andrew Griffiths. Greatest thanks to all collaborators, it was a long and winding journey but it paid off!

Very interesting topic for doing a phd, highly recommended

We have a PhD position on phosphate-driven non-equilibrium assemblies funded from European Research Council (ERC) at FIT - Uni Freiburg Universität Freiburg Freiburg Chemistry Institutes. Deadline for application is 01/08/24. More information can be found here: static1.squarespace.com/static/5fc3928… RT appreciated!

Reactive Martini applied to simulate ring formation inside condensates. Great work from Chris Brasnett in collaboration with the SijbrenOttoLab. Published in Comm. Chem. rdcu.be/dMF8N

Our latest publication is out now. This collaborative effort between Siewert-Jan Marrink group and SijbrenOttoLab explores the dynamics of chemical reactions inside condensates and their potential role in the origin of life. Thanks to all authors specially Chris Brasnett ! nature.com/articles/s4200…

Probe the non-enzymatic macrocyclization reaction of benzene-1,3-dithiol in the presence of peptide condensates by reactive Martini simulations, reported by Siewert-Jan Marrink SijbrenOttoLab Chris Brasnett nature.com/articles/s4200…

Coacervates can accelerate (bio)chemical reactions and direct their outcome. In our new review by Iris Smokers we detail how their unique properties allow them to function as catalytic microcompartments at the origins of life. Have a look here: pubs.acs.org/doi/10.1021/ac…

Our latest paper is out in Nature Chemistry! We explored how fueled chemical systems can drive nanoscale self-assembly and motion at the macroscale. Congrats to all authors, SijbrenOttoLab, and Kai Liu! nature.com/articles/s4155…

And the last of 3 SijbrenOttoLab papers within 24h! Biological principles are valid only for biological systems? Don't bet on that. We found synthetic replicators literally dying out when in competition, or coexisting if they have different food preferences. nature.com/articles/s4155…