This is the psychonaut content we need and deserve

What. Wild

Fab work by Kate Godfrey et al. here: An investigation of acute physiological and psychological moderators o... sciencedirect.com/science/articl…

Transcend Scores Breakthrough Therapy Designation for Methylone Transcend Therapeutics has been granted Breakthrough Therapy Designation (BTD) by the FDA for its methylone candidate (TSND-201) for PTSD. Read more in Bulletin 203: psychedelicalpha.com/news/p%CE%B1-p…

Important work from Luke Jelen. The opioid system is involved in ketamine's antidepressant effect - well powered study with insight into the mechanism. Esp for ketamine responders, unequivocal reduction in efficacy when pretreated with naltrexone

I have many things to say about this extraordinary trauma release practice... thread incoming

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial onlinelibrary.wiley.com/doi/abs/10.111…

Treatment of depressive and negative symptoms in individuals with schizoaffective disorders using serotonergic psychedelics: a case report and a nice review of the sparse literature on risks of psychedelics w/people who have bipolar or schizo-spectrum dx jpn.ca/content/jpn/50…

A Phase 1 study of psilocybin’s safety and tolerability in patients with chronic stroke is getting underway at Johns Hopkins University, led by Gül Dölen and colleagues. Read more in Bulletin 204: psychedelicalpha.com/news/p%ce%b1-p…

"This entails that all adults have the freedom to recreationally use psychedelics without restrictions and that communities provide harm reduction and benefit enhancement services to support this freedom." journals.sagepub.com/doi/pdf/10.117…

Exploring the potential psychological predictors associated with changes in depression, anxiety, and well-being following naturalistic psychedelic use sciencedirect.com/science/articl…

Guys. That is not san pedro

Interesting head to head study (with unsurprising findings ;-) Understanding the Psychological Effects of Psilocybin and 3,4-Methylenedioxymethamphetamine in a Non-Clinical Population medrxiv.org/content/10.110…