Malaria-induced innate immune modulation of an atypical cell-type plays a substantial role in driving and maintaining #immunity against #malaria in #Ugandan children, reports a study from Prasanna Jagannathan’s Prasanna Jagannathan team Stanford University University. genengnews.com/topics/transla…

“What [cancer] patients are looking for is to know, to the best of their knowledge, where they fit into the response expectations,” says Robert Nagourney, MD. His team measures #cancer cells responses to a variety of drugs to predict patient responses to therapy. genengnews.com/resources/biot…

Seed T cell progenitors in transplants are key in sustaining #GVDH diseases report scientists UPMC and Uni Heidelberg, overturning prevailing concepts. genengnews.com/insights/susta…

The world we perceive may depend as much or more on our cerebral cortex than sensory inputs that arrive at the cortex through the thalamus. Elly Nedivi and her team at Massachusetts Institute of Technology (MIT) found thalamic inputs into cortical layers 2/3 are rare, weak and diverse. genengnews.com/neuroscience/v…

A new study from Strata Oncology validates the clinical utility of a pan-solid tumor #biomarker, IRS (Immunotherapy Response Score), that predicts the benefit of anti-PD-1/PD-L1 checkpoint inhibitor monotherapy in patients with advanced solid #tumors. genengnews.com/news/strata-on…

#ALS research gets a fresh impetus with an open resource that includes clinical and omics data linked to #motor neuron samples derived from ALS patients and healthy subjects. The work is a collaborative effort of Cedars-Sinai, UC Irvine and AnswerALS. genengnews.com/neurological-d…

asarkar.substack.com/p/ghosts-of-ot…

A drug instead of surgery may correct #limb length in patients with a rare #skeletal syndrome, a preclinical study from Nationwide Children's Hospital and Van Andel Institute (VAI) indicates. genengnews.com/topics/transla…

Jumping genes wire #fat distribution patterns affecting #metabolic health, particularly in #women, a new study from Marcelo Nobrega’s team at the The University of Chicago shows. genengnews.com/topics/drug-di…

Breakthroughs in #biotechnology, health care, and economy must be complemented by an earnest commitment to #SocialJustice and #healthequity, to improve the lives of patients with #sicklecelldisease. liebertpub.com/doi/epdf/10.10…

An ionizable lipid nanoparticle formulation containing mRNA for VEGF-A can be directed to the cells in the placenta during pregnancy to dilate blood vessels and treat #preeclampsia, claim Kelsey Swingle and Michael Mitchell, from Penn. genengnews.com/topics/transla…

Mouse model studies and #RNA #sequencing enable Yadong Huang, MD, PhD, and his team at UC San Francisco to uncover evidence indicating ApoE4 removal as a potential treatment strategy for #Alzheimer's disease. genengnews.com/topics/drug-di…

It makes neuro-mechanistic sense to opt for #sex over #food, shows Tatiana Korotkova Tatiana Korotkova and her team anne petzold, anne petzold, Universität zu Köln, offering insights into #obesity and #eatingdisorders. genengnews.com/neurological-d…

An open-source, user-friendly, #ArtificialIntelligence driven #software called LabGym from scientists University of Michigan automatizes animal #behavior analysis in various model systems. This could be a boon to life scientists across the spectrum. genengnews.com/artificial-int…

Nicholas Spitzer's lab at UC San Diego Health identifies neuroanatomical and neurochemical signatures of generalized #fear triggered by acute #stress, as experienced by individuals with #PTSD. linkedin.com/pulse/fear-tri…

Wilhelm Hueper, a DuPont scientist ostracized in the 1930s for talking frankly about chemicals and cancer, knew the score: "The only thing [corporations] understand is jail and bad publicity." Read more: beacon.org/The-Cancer-Fac…

Wonderful poems by Amit Majmudar. I particularly enjoyed 'Matriarchy': oneartpoetry.com/2022/12/04/thr…

I'll be attending the amazing Actionable Insights: Seeding Our Way Forward in AI. Let me know if you're planning to attend so that we can say Hi! 👋 Or register now and join me at the event! whova.com/portal/registr… via #Whova event app whova.com/portal/registr…

A hypercompact plant genome editor expands the current toolkit and improves the ability to target genomic loci hitherto inaccessible. Kutub ICAR-Central Rice Research Institute genengnews.com/topics/genome-…

In his new #book, Alexander Hutchison, takes a pragmatic look at the science, history, ethics, and economics of #doping in #sports provoking us to rethink age-old #controversies. linkedin.com/pulse/ethics-e…