Figuring out the wide range of immune cells, cytokines, and functions of cytokines in those cells, has been a major challenge in cytokine-based therapies. Find out about a potentially well-organized “Immune Dictionary” that will help tackle the issue.
antibuddies.org/2023/12/24/a-p…

The #ImmuneDictionary holiday party with my lab and our friends. Happy Holidays!

What impact does #ArtificialIntelligence have on #medicine and #science ? Nobel Laureates Aaron Ciechanover, Avram Hershko and Michael Levitt discussed this with Shwetak Patel, Lindau Alumni Ang Cui, Ph.D., AderonkeSakpere and moderator Bart de Witte: ow.ly/AXpy50Qij4O

My new favourite dictionary! nature.com/articles/s4158…

Oh my gosh, this is fantastic!!! Learn how every immune cell type responds to every cytokine. BRAVO! 👏👏👏

Ang Cui, Ph.D. nature Amazing work and so meticulously detailed. Can't wait to see all the research that will get a boost from being able to reference and make use of this incredible body of work. You've truly advanced many fields of science by making this resource available to all. Well done!

Very excited by our results nature showing that IL4R signaling is strongly enriched in myeloid cells that infiltrate mice and lung cancer lesions nature.com/articles/s4158…

This is a fantastic landmark paper nature I cannot help sharing. It really helps us understand the diversity of immune cells, esp how they polarize with the diverse array of stimulating cytokines…

nature.com/articles/s4158…

Who wants to join the #ImmuneDictionary project? Multiple exciting projects are ongoing and I'm hiring 1-2 more computationalists and 1-2 more experimentalists to start ASAP.

Exceptional candidates at all levels (postdoc/grad/staff/visitor) are considered. Email me with your CV

And Spatial VDJ is out! More to follow, but for now, joy and gratitude for the privilege to work with the wonderful Kim Thrane Qirong Lin Jeffrey Mold Jonas Frisén Joakim Lundeberg and many more collaborators. Karolinska Institutet SciLifeLab KTH Royal Institute of Technology science.org/doi/10.1126/sc…

A nature paper presents the Immune Dictionary and its companion software, which is based on an analysis of in vivo responses to 86 cytokines across more than 17 immune cell types. go.nature.com/47JCq1d

Dictionary of immune responses to cytokines 👇
Even a single cytokine, such as IL-1β, can trigger distinct responses in each cell type to create a coordinated multicellular immune response. nature.com/articles/s4158…

Dictionary of immune response to cytokines. On the way to build a full immune dictionary bits by bits with single cell data! nature.com/articles/s4158…

Breaking news: immune system is even MORE complex than previously thought 😂
Fortunately, this very cool paper and companion tools shed some light on how to work with this mind-blowing complexity.
Huge work by Ang Cui, Ph.D. and colleagues! Will be talked about for years to come. 👍

AMAZING tour-de-force science out today in nature which I am sure all of us will be pouring over for our own experiments.

This is so important

Absolutely amazing work and title “Dictionary of #immune response to cytokines at single cell resolution. Thank you for sharing this phenomenal resource! Ang Cui, Ph.D. nature

This work deserves the Nobel prize, gosh it’s so beautiful and inspiring 😭🫶🏻✨