Characteristics of blood–brain barrier heterogeneity between brain regions revealed by profiling vascular and perivascular cells | Nature Neuroscience nature.com/articles/s4159…

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye! The dye is tartrazine, used in Doritos! science.org/doi/10.1126/sc…

Ever wonder if small injuries to capillaries have lasting consequences? Our work exploring this question is now out! None of this would have been possible without the help of some brilliant minds - Cara Nielson @sosamariaj Orla Bonnar Andy Shih pnas.org/doi/10.1073/pn…

1/4 We are thrilled to announce that our 🌍 collaboration has resulted in a paper in JCBFM. @Gazz4_Science Catherine Foster Brad Sutherland University of Tasmania @SeattleChildrens University of Copenhagen doi.org/10.1177/027167…

Neurovascular coupling and CO2 interrogate distinct vascular regulations | Nature Communications nature.com/articles/s4146…

Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia | Neurology neurology.org/doi/10.1212/WN…

Inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia. Congrats Dave Attwell, Nils Korte and team! 🤩 nature.com/articles/s4159…

Super excited to share our work: inhibiting Ca2+ channels in Alzheimer’s disease model mice relaxes pericytes, improves cerebral blood flow and reduces immune cell stalling and hypoxia. nature.com/articles/s4159… 1/6

In vivo evidence for the functionality of #Pericyte #TunnelingNanoTube in Retina😎 Inter-pericytic TNT connects capillaries of the same or different orders Transfer Ca2+ signals & Mitochondria Disrupted by ischemia (retinal central artery ligation, focal photothrombosis, OGD)

PhD and/or Postdoc openings in our lab. Get in touch if you are at SFN and want to discuss.

Plasma proteomics identify biomarkers and undulating changes of brain aging | Nature Aging nature.com/articles/s4358…

Endothelial cells as key players in cerebral small vessel disease | Nature Reviews Neuroscience nature.com/articles/s4158…

Online now: Loss of endothelial CD2AP causes sex-dependent cerebrovascular dysfunction dlvr.it/THj72w

🚨 #HotTopic : Pericytes at the BBB aren’t one-size-fits-all! 🧠✨ Discover how PC1 supports BBB #homeostasis via hedgehog signaling, while PC2 responds to #disease with phagocytosis & immune infiltration: 👉🏻journals.sagepub.com/doi/full/10.11… #ISCBFM #Neuroscience #Pericytes #Brain

📣 For vascular biologists and mechanobiology aficionados, this is a meeting you don't want to miss! Gordon Research Conferences - Biomechanics in Vascular Biology and Disease (grc.org/biomechanics-i…) 💡 Abstract Submission now open (deadline March 10th)!

Brain pericytes and perivascular fibroblasts are stromal progenitors with dual functions in cerebrovascular regeneration after stroke | Nature Neuroscience nature.com/articles/s4159…

Excited to share that I'll soon be moving back to Edinburgh to start my own lab, as part of the BHF-UK DRI Centre for Vascular Dementia Research! The Rajani Lab will be recruiting soon, so keep your eyes peeled...

Delighted to share our review in Nature Reviews Neuroscience! We examine growing evidence that vascular dysfunction contributes to cognitive decline in ageing and dementia, and argue that preserving/restoring CBF should be central to future therapies. nature.com/articles/s4158…