Risankizumab vs. Ustekinumab for Crohn’s Disease with anti-TNF failure! 🧵🔥 A head-to-head trial comparing these two IL-23 inhibitors in moderate-to-severe Crohn’s disease (SEQUENCE Study, NEJM 2024). Let’s dive in! ⬇️

🧵 ESCAPE Trial: Early Surgery vs. Step-Up Approach in Chronic Pancreatitis 🏥🔬 Can early surgery improve outcomes in painful chronic pancreatitis (CP) compared to the conventional endoscopy-first approach? Let’s dive into the ESCAPE trial findings! 👇

The much arduous journey of terlipressin to finally get the FDA approval is fascinating. After two failed trials OT-0401 (2008) and Reverse (2019), the CONFIRM trials finally hit the spot. Loved this 🧵

1/🧵 Can early liver transplantation (LT) save lives in severe alcoholic hepatitis (AH)? Traditionally, a 6-month abstinence rule was mandatory, but recent data challenges this. Let’s dive into the evidence, including ELITA & SALT trials! 👇 #LiverTwitter #Transplant

🧵Why does cirrhosis cause Caput Medusae, but EHPVO doesn’t? A thread 1/Caput Medusae=Dilated paraumbilical veins radiating from the umbilicus due to portal hypertension. But why does it happen in cirrhosis and not in extrahepatic portal vein obstruction (EHPVO)?🤔 #MedTwitter

Each day, new lesson!

🧵 The END-PAC Score: Identifying Pancreatic Cancer in New-Onset Diabetes (NOD) NOD in older adults can be an early sign of pancreatic cancer. But how do we separate benign diabetes from cancer-related diabetes? Meet END-PAC, a simple risk stratification tool! 🚀 ⬇️ #MEDTWITTER

1️⃣: 🚨MAN Criteria – Can we predict who will respond to PPIs in GERD? 💊Up to 40% of GERD patients don’t improve with PPIs! 📊MAN Criteria helps identify true responders vs. those needing further evaluation. A deep dive into MAN Criteria and its origins! 🧵 ⬇️ #Gastroenterology

🚨 Nor-UDCA vs. UDCA: What’s the difference? A 🧵 on why Nor-UDCA is a potential game-changer in cholestatic liver diseases! 👇 #LiverTwitter #MedTwitter

MD Convocation ✅ with the real OGs of Medicine Nikhil Vasudeva Amit Chavan Parth @ Kartik Aggarwal

TRUTH REMINDER : Your muslim friend didn't post a single story condemning Pahalgam Terror Attack. That same muslim friend posted uncountable stuff for Palestine, Rafah and Gaza.

The IMF is a sponsor of terrorism. Repost if you agree.

Hello IMF, update your logo.

This makes sense! Shiv Aroor explained why today’s ceasefire happened beautifully in a quick 90-second video.

When I founded RCB it was my dream that the IPL trophy should come to Bengaluru. I had the privilege of picking the legendary King Kohli as a youngster and it is remarkable that he has stayed with RCB for 18 years. I also had the honour of picking Chris Gayle the Universe Boss

The old habit of taking credits hasn't died. First from the banks, now IPL trophy.

A Punjabi family on a flight was extremely loud throughout and left the cabin in a mess — food, wrappers, and shoes scattered all over. It was embarrassing to watch. Basic etiquette while flying shouldn’t be too much to ask. pic.x.com/DN9IrE8ibi

Loved the podcast on IBD Two Guys Talking $it. Thank you for the insightful episode and as always, learning from Beatriz Gros is fun. Keep 'em coming.

Since its release 11 years ago, just one hour and 31 minutes have passed on Miller's planet in Interstellar.