Dr. Amber Habowski
@amberhabowski
Postdoctoral Fellow Tuveson Lab - CSHL #PancreaticCancer #Therapeutics #Organoids #Bioinformatics #Intestine #RNA #StemCells
ID: 1224587296948674560
https://www.linkedin.com/in/habowski/ 04-02-2020 06:55:50
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Congratulations to Cold Spring Harbor Laboratory Director Dr. David Tuveson, who was elected to the National Academy of Medicine! He is being recognized for his ground-breaking work and leadership in the field of pancreatic cancer research. cshl.edu/david-tuveson-… #PancSM #PancChat
1) PASS-01 #Pancreatic #Cancer Collective New Therapies /PASS-01 trial accruing! Amazingly successful at generating organoids/variations in sensitivity to panel of chemo/supported by Lustgarten Foundation & Stand Up To Cancer presented @ #SU2CSummit2023 Let's Win Pancreatic Cancer 💜 Pancreatic Cancer UK PanCAN
PASS-01 dream team working to improve #PDAC patient outcomes and revolutionize personalized medicine #Organoids Stand Up To Cancer #SU2CSummit2023 Grainne O'Kane #TuvesonLab
Excited to be joining the American Cancer Society family and to advance therapy options for #PDAC patients! ACS Research Cold Spring Harbor Laboratory #postdoc #Organoids #PersonalizedMedicine #TuvesonLab
PASS-01 trial #PDAC #ASCO24 ➡️rand ph2 mFFX vs.GnP ➡️WGS/RNA/PDO/CTCs/ctDNA ✅PP PFS 5.5 (GnP) vs. 4.0mths (mFFX) ➡️PP ❌gBRCA/PALB2 >KRASWT in GnP ➡️MTB directed 2nd line ➡️ GnP remains a backbone for drug dvp ➡️basal-like unmet need Proud Dr. Amber Habowski as translational leads
Day 3 poster session at #AACRPan24 featured two PASS-01 posters! Dr. Amber Habowski described preliminary results from #PDO work in the Tuveson lab, and Grainne O'Kane showed #genomic and #transcriptomic results in #pancreaticcancer patients. #PDAC
Extremely proud of the correlative work done by Dr. Amber Habowski from Cold Spring Harbor Laboratory on the Stand Up To Cancer - Lustgarten Foundation PASS-01 study; the results of which continue to provide a wealth of information for the treatment of #pancreaticcancer. #aacr25 #PDAC
Two important randomized trials in #PancreaticCancer published: 1st PASS-01 in metastatic cancer comparing FOLFIRINOX to Gem/Abraxane (Journal of Clinical Oncology) 2nd PREOPANC-2 in resectable/borderline resectable cancer comparing neoadjuvant FFX versus Gem/CRT (The Lancet Oncology) OncoAlert ⬇️
PASS-01:ph II mFFX v GnP;#PDAC denovo met ds; excl gBRCA/PALB2 ➡️no clinically sig diff GnP v mFFX ➡️basal-like poor OS-mPFS on mFFX 3 mths ➡️54% receive 2nd line; mOS<6mths ➡️PDOs/ctDNA to come Dr. Amber Habowski 1st-line biomarkers essential-RAS &🤞subtype doi.org/10.1200/JCO-25…