For nearly 2 decades, Alzheimer’s disease (AD) “genome-wide” association studies only covered the autosomes. Today we unveil the X chromosome and prioritize SLC9A7, a.k.a. NHE7, as an AD risk gene. Article: jamanetwork.com/journals/jaman… Editorial: jamanetwork.com/journals/jaman…

Does the brain change during pregnancy? You bet it does. How about doing 26 MRI scans on a single person pre-conception to 2 years post-partum. WOW! Laura Pritschet and colleagues nailed it with their new paper in Nature Neuroscience. Key Points: - The authors point out that pregnancy

It's finally here! Beyond excited to share our new paper: B cells drive neuropathic pain–related behaviors in mice through IgG–Fc gamma receptor signaling science.org/doi/10.1126/sc…

Exciting first day at #ReThinkNeuroimmunology BIG Center @WashU Brain-Immune Communication Lab

An important study by F. Eun-Hyung Lee's team shows that long lived plasma cells (the source of long-term circulating antibodies) fail to establish after mRNA vaccination (even combined with SARS-CoV-2 infection). 🧵 (1/) nature.com/articles/s4159…

These findings are from a study in Nature Neuroscience which identified common genetic variants that affect rates of brain growth or atrophy in the first genome-wide association meta-analysis of changes in brain morphology across the lifespan. nature.com/articles/s4159… 2/9

Neuropeptide signalling orchestrates T cell differentiation nature nature.com/articles/s4158…

Corning now offers sterile tips that come in a paper container, thus generating less plastic waste!

❇️ Ce 22 octobre, l’Institut illumine ses bâtiments en vert pour soutenir le syndrome Phelan-McDermid (PMS), un trouble génétique associé à un retard du développement et à l’autisme. Les recherches sur SHANK3 ouvrent la voie à des essais cliniques prometteurs. 💚 #ShineGreen

Our latest paper on neuronal resilience. The apoptotic pathway is activated as a transient pulse in neurons even with continuous apoptotic stimulus. Neurons prepare for survival even when they activate apoptotic signaling. Congrats Keeley and others!! nature.com/articles/s4141…

📽️🇫🇷✅Please vote for 'Forgotten'✅🇫🇷 📽️ We are pleased to have supported this short powerful film by Association CLE, directed by Alexandre Lenis for the Nikon Film Festival festivalnikon.fr/video/2024/7558 #CovidLongPediatrique #LongCovidKids #LongCovid

#WeekendRead! #LipidPower! Hugues &co show Nature Communications that lymphatic endothelial cells modify cholesterol into oxysterols, blocking PPARg in intratumor macrophages & monocytes, making them more inflammatory thus potentiating anti-tumor T cell responses!! nature.com/articles/s4146…

Pyrolysis gas chromatography-mass spectrometry reveals the presence of micro- and nanoplastics in human kidney, liver, and brain tissue samples from 2016 and 2024, with higher proportions found in the brain nature.com/articles/s4159…

It’s no secret that we do our best work when it's less like work and more like a joy. That’s what we have in mind for Woodstock Night Science. The idea is to have the most fun conference possible so that good ideas flow and we all get inspired. That's needed now more than ever!

Granzyme K+ CD8 T cells slow tauopathy progression by targeting microglia nature.com/articles/s4159…