Very excited to share our 1⃣st publication from the lab - the development of near PAMless CRISPR-Cas9 variants. Huge congrats to Russell Walton (🙌), Kathleen Christie, and Madelynn Whittaker for their tireless work. Brief thread 👇. #CRISPR #druggablegenome science.sciencemag.org/content/early/…

Molecular biologist thinking he’s an epidemiologist x.com/TayyabaWaqas94…

Some scientists looking at left-handed DNA x.com/ChronicOG_2nd/…

Yay - our paper on Structure-mediated RNA decay (SRD) is officially out! We discovered a new paradigm to read RNA. Instead of defined sequence or structure, SRD detects density of RNA base-pairing. SRD works in both coding and noncoding RNAs. Free access: authors.elsevier.com/a/1aqog3vVUPDd…

An interesting new role for nucleolar-centromere contacts: regulation of satellite DNA transcription. A fun collaborative project with Leah Bury (Leah Bury), Brittania Moodie, Liliana McKay, and Iain Cheeseman (Iain Cheeseman).

Perspective written with the talented Natalie Papanicolaou on the functional characterisation of noncoding variants associated with common diseases and future therapeutic targets. tinyurl.com/y7qxdrqt

Proud to have taken part in a project with so many possible biological implications! It's been a long journey on a very bumpy road but only the mix of talent and resilience from @muju79 made it possible. Great work Giovanni!

We are recruiting. If you are a computational biologist interested in single-cell analysis and transposable elements then apply now! Great team and great conditions Lund Stem Cell Center. Please RT! nature.com/naturecareers/…

Do you also feel like saying after paper rejection: "Hello, my name is Yossi Buganim, you killed my paper prepare to die!" Or is it only me? 🤔

Researchers have designed an #mRNA vaccine that delayed the onset of and reduced the severity of multiple sclerosis-like disease in mice. The vaccine restores the body’s tolerance to its own proteins, suppressing the disease's immune overreactivity. ($) fcld.ly/s6xsa24

Hiring! We are seeking for highly motivated scientists for a remote Junior Bioinformatician position. ScitoVation is a premier startup company with the mission of developing approaches to understand the impact of small molecules & chemicals on our health. tinyurl.com/7y9p2dt4

🎤Don’t miss Alessandro Bonetti Alessandro Bonetti at Cambridge Biochemistry the 20 Mar. at the RNA Club He'll dive into the fascinating world of lncRNAs, explaining why they're such exciting therapeutic targets and how his pioneering work with RADICL-seq is uncovering new insights into RNA biology

Download the topshelf records 2011 Label Sampler! 68 songs for FREE! http://tpshlf.co/tsr2011