The AMS team have had a busy day updating the antibiotic guidelines on MicroGuide, 👀 keep a lookout for our exciting new update that will support everyone with their antimicrobial prescribing #walsallandproud Walsall Healthcare

Another fantastic C.diff event with great attendance from our colleagues Walsall Healthcare Well done and thank you Infection Prevention & Control WHT @stefano_oggiano @JessicaBartlam Amy Cartwright Kitty Dhingra

Come visit our stand today! We have had been raising awareness for World AMR Awareness Week down by Costa, join us to learn more. Kitty Dhingra and Liz have been doing an amazing job today #WAAW #WAAW23 Walsall Healthcare Aiden J Plant Infection Prevention & Control WHT @IPC_Amy Karamjit Badyal

At the end of #WAAW we were joined by Lisa Carroll and @IPC_Amy reviewing every patient on an antibiotic on Ward 9&10 on “time out” ward round, we ✅ reviewed cultures and sensitivities ✅ checked it’s the right antibiotic ✅ IV to PO switch ✅ stopped and escalated abx

Wow what an amazing Day 1 of #MRDP24 - great speakers and attendees. Thanks for inviting me to speak - I could’ve gone on for hours 🫢

A great week of infection consults done ✅ 🟢 managing measles 🟢 Hep A + enteric fever co-infection 🟢 paediatric SAb with multifocal arthritis 🟢 dalbavancin for staphylococcal IE 🟢 workup for PUO 🟢 recurrent GNB-bacteraemia 🟢 facet joint SA AMS team WHT, Infection Prevention & Control WHT.

Is IV Clarithromycin better than oral? A question asked while on micro rounds, a great chance to dispel a myth: 💊It is highly lipophilic resulting in excellent tissue penetration irrespective of route 💊It has 20 x greater concn in pulmonary epithelial tissues than in serum

Our weekly infection MDT journal club📚 Karamjit Badyal Kiran Bhatt AMS team WHT Today’s paper: 1️⃣ rate of rec CDI still 25% 2️⃣ predicting rec CDI is tricky 3️⃣ CDI Rx distorts the microbiome 4️⃣ (any) Abx use 10d prior to CDI Dx was protective of rec CDI⁉️ rdcu.be/dOESv

A positive C diff test (TOX or PCR) does not = anti-CDI treatment automatically. #microbiome

Current guidelines recommend adjunctive gentamicin for the treatment of Enterococcus faecalis IE despite a risk of toxicity. The authors sought to revisit the evidence for adjunctive therapy in EFIE and to synthesize the comparative safety and effectiveness of AG Vs Ceftriaxone.

AMP + CRO is our standard for E faecalis IE

【If, When, and How to Use Rifampin in Staph PJI】Clinical Infectious Diseases 2021 👉N=669, multicenter 👉Failure 32% w RIF vs 54% w/o RIF 👉RIF use: success↑ 👉RIF start within 5 days after debridement: failure↑ pubmed.ncbi.nlm.nih.gov/33970214/ Mayo Clinic Infectious Diseases #OrthoID #Teachingrounds

Takahiro Matsuo (Taka), MD Clinical Infectious Diseases Mayo Clinic Infectious Diseases Great study - confirms our practice... we aim to start RIF for all (sensitive) staphylococcal PJI asap after debridement. Our choice companion drug is DOXY! Aiden J Plant AMS team WHT

【The Role of Antibiotics in the Cement Spacer】Clinical Infectious Diseases 2019 🤔Question from Ortho colleague 👉N=344, 2-stage PJI 👉Glycopeptide to the cement spacer ↓+cultures during reimplantation/↓failure due to CoNS pubmed.ncbi.nlm.nih.gov/30281077/ Mayo Clinic Infectious Diseases #OrthoID #Teachingrounds

Is there a 10% cross reactivity between penicillins and cephalosporins? ❓A common query at the Pharmacy counter Cephalosporins and penicillins both have a beta-lactam ring, additionally some cephalosporins and penicillins share identical side chains 1/5

We ask that every patient Walsall Healthcare is asked about their penicillin allergies and are assigned a PEN-FAST score so we can open up the best antibiotic treatment options Aiden J Plant Kiran Bhatt #antimicrobialstewardship

Interesting Journal club paper discussed today...Vaginal probiotics as supplementation for prevention of recurrent UTI! Need another study in Post menopausal women with "recurrent " UTI symptoms. Aiden J Plant AMS team WHT pubmed.ncbi.nlm.nih.gov/38084984/

Another week of crazy interesting infection consults 🧐 - neurologically focused 🧠 ✅ post neurosurg meningitis ✅ VP shunt ventriculitis ✅ Bickerstaff’s encephalitis post-Campy ✅ Hep E induced polyradiculopathy AMS team WHT Kiran Bhatt Kitty Dhingra Karamjit Badyal

🤔 Is C. diff diarrhoea associated with greater social deprivation in England? 📈 Since the COVID-19 pandemic, the incidence of CDI has increased, particularly for community-acquired disease. What is driving this epidemic? Aiden J Plant @stefano_oggiano ow.ly/bya050T9sTi

WILL PEOPLE PLEASE STOP CITING KUMAR ET AL CRIT CARE MEDICINE 2006 AND CLAIMING a 7.6% MORTALITY DECREASE PER HOUR WITH ANTIBIOTICS. THIS IS COMPLETELY NOT TRUE AND HAS BEEN KNOWN FOR YEARS! god this zombie fact WILL NOT die. There are RCT's on the topic!! No effect!!