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2❤️human devbio projects later😉, Jennifer Mitchel and I are excited to share our review on the biological mechanisms regulating the mechanical properties of tissues in cancer and morphogenesis. Thanks for the great discussions 🤓🙂🤩 #collectivemigration doi.org/10.1016/j.ceb.…

What’s the link between Origami and morphogenesis? This is the world of Actuation, I’m Abdel Rahman Abdel Fattah, and I’ll share with you insights, experiments and an outlook on how epithelia use mechanical forces to gain geometrical and functional complexity.

Exciting breakthrough: A new microfluid-based human pluripotent stem cell model now allows researchers to accurately model both the rostral-caudal and the dorsal-ventral features of early human central nervous system development. rdcu.be/dzF73

New #review on "Shaping Epithelial Lumina under Pressure" now published #BiochemSocTrans Portland Press! Matt Bovyn and I review lumen formation mechanics and discuss the emerging role of nonlinear mechanics in the elongation of tubular lumina. doi.org/10.1042/BST202…

Paper is now out in eLife - the journal 🐵🦓🧠🐈🦔🐕🦇🦭🦥 cerebellar folding amazingness! elifesciences.org/articles/85907 together with a summary article of our work elifesciences.org/articles/93122 & a press release elifesciences.org/for-the-press/… with Roberto Toro [email protected] r3rt0.bsky.social Nicolas Traut Dr. Alexandra A. de Sousa Sofie Valk Institut Pasteur, since 1887

Organ-on-a-chip is one of the Hot Topics at microTAS with keynote speakers Dongeun (Dan) Huh (Penn) and Roger D. Kamm (Roger D Kamm Massachusetts Institute of Technology (MIT)), and session chairs Milica Radisic (Milica Radisic University of Toronto) and Adrian Ranga (Adrian Ranga KU Leuven). Abstract Deadline: May 14th.

📢New preprint alert for vascular biologists, bioengineers and living matter physicists! " Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics. " Or the story of what happens to a living tissue when you pull on it ? 💪

Hes genes are dynamically expressed in many tissues. But how do dynamics differ between tissues and are they always oscillatory? We have addressed this question in the context of the developing embryo, where somites and neural tube form side-by-side. biorxiv.org/content/10.110…

📢📢📢How can we obtain a robust outer radial glia (oRG) population in 🧠organoids from guided differentiation? Exogenous LIF does the trick. Our new paper shows that cortical pericytes are among the cell types secreting LIF. Adding pericytes to cortical organoids recapitulates

1/n Today in Science Magazine: ‘Risk of meningomyelocele mediated by the common 22q11.2 deletion’. science.org/doi/10.1126/sc…

Time is now to showcase your organoid work! Five days left to submit your abstract to our Spring Meeting “Focus on organoids”, taking place in Leuven in de Hoorn on June 7th. Register on bscdb.be/spring-meeting -organised by Laurent Nguyen @EveSeuntjens Adrian Ranga Pierreux Christophe

Now out! I'm beyond thrilled to share our method for dynamically measuring neurulation forces. We hope that our addition to the toolkit will push forward the quantification of living tissue mechanics. Elvassore Lab Gabe Galea Università di Padova Developmental Biology & Cancer Marie Skłodowska-Curie Actions nature.com/articles/s4156…

Cell Cycle Chicken neural tube. These world first chicken embryos are a feature of #EGGED2024! EMBO Events NARF The Roslin Institute Royal Society of Edinburgh. E

Ever wondered how stem cells ensure a balance between cell fates in the gut?⚖️Turns out, they’ve got rhythm!🎶Our latest research reveals that NOTCH-driven oscillations regulate stem/progenitor cell abundance and specify secretory subtypes. Check it out: biorxiv.org/content/10.110…

In this article, we show that ‘embryonic regulation’, the ability of embryos to adapt to perturbation (and to cope to inherent variability), is driven by self-organized tissue mechanics, upstream of Gdf1, whose expression is sufficient to trigger embryo formation in avians.

Our new study updates 50-year-old models of developmental #neuralcrest cell migration, using mosaic variant analysis in human, mouse and quail. Melanie D. White, also @melaniedwhite.bsky.social Harry Keng Ioi Vong Xiaoxu Yang biorxiv.org/content/10.110…

Happy to proudly share that my first first-author work is finally published Nature Communications nature.com/articles/s4146…. A lot of sweat and tears went into this and I hope our findings on the role of cell forces in recruitment of cells in the context of CCMs make for an enjoyable read.

TiFM2.0 - Versatile mechanical measurement and actuation in live embryos biorxiv.org/content/10.110…

Long overdue BBC News - Folic acid added to flour to lessen birth defects bbc.com/news/articles/…