Very proud of this piece of work where we look at the aetiology of antidepressant side effects in a large sample: nature.com/articles/s4385…

Campos et al. study the genetic aetiology of antidepressant side effects using data from the Australian Genetics of Depression study ow.ly/SfMw50GOyIr

And if you want this view from your next office, we have several postdoctoral opportunities in the SGDP Centre KCL, advertised and coming out shortly.

Today I saw the impact that AlphaFold is having on speeding up drug discovery firsthand:

A swimming 🏊‍♀️/ academia 👩‍🎓 tale I swim most mornings in our local pool. It’s empty between the committed 6am-ers, and the post-school-run parents. A lovely Zen-like start to the day. [And if you need to ask me a big favour, choose to meet me at 8.30 or 9] 1/6

Proud to announce a #PhDposition in genetic epidemiology at UiO - Det medisinske fakultet: jobbnorge.no/en/available-j… The candidate will be working on a Norges forskningsråd project with david_mf_evans Ben Brumpton Bjørn Olav Åsvold @DeborahLawlor2 and me using data from @theHUNTstudy and UK Biobank Please RT!

Review of polygenic predictors of anti-depressant response identifies 11 paper. Modest effects of diverse polygenic scores associated with response, but larger studies needed. See also our PGC Consortium a/d GWAS + polygenic paper doi.org/10.1016/j.bpsg… sciencedirect.com/science/articl…

Drug combinations can overcome therapy resistance but the number of possible combinations is vast. Today we published @nature a study using pharmacological screens in cancer cell lines and multi-omics analysis to identify effective combinations in defined molecular backgrounds.

Together with Scipod we've made a podcast about our Nature Communications paper: #MendelianRandomization study of #maternal influences on #birthweight and future #cardiometabolic risk in the #HUNTcohort Listen here or where you get your podcasts: scipod.global/do-maternal-in…

Dr Loic Yengo of Institute for Molecular Bioscience has been awarded the Ruth Stephens Gani Medal 2022 for outstanding contributions to research in human #genomics to address questions about the causes and consequences of human behaviour. UQ News #Honorifics22 science.org.au/supporting-sci…

Elon Musk should buy 23andMe and release all GWAS summary statistics

Enjoyed this great NYT article on APOL1, its association with kidney disease in African Americans and the related drug development efforts. It's story telling time. Let's dive into the story of APOL1 from discovery to therapeutics. 🧵 nytimes.com/2022/05/17/hea…

Wonderful that our AGDS data could contribute to this!!

Very happy to share this pre-print from the PGC Suicide Working Group and the Million Veteran Program, “Genome-wide association study meta-analysis of suicide attempt in 43,871 cases identifies twelve genome-wide significant loci” Huntsman Mental Health Institute PGC Consortium medrxiv.org/content/10.110…

Gather round, Twitter folks, it's time for our beloved **Alice's adventures in a differentiable wonderland**, our magical tour of autodiff and backpropagation. 🔥 Slides below 1/n 👇

Our article summarising some of the key challenges for the field of psychiatric genetics is out now in Nature Genetics. As always, an absolute pleasure to write this with Eske Derks and @zac_gerring @QIMRBerghofer nature.com/articles/s4158…

UQ Science Congratulations to Dr Yengo for being awarded the Ruth Stephens Gani Medal for his contributions to human #genetics. The medal honours the contribution to science in human cytogenetics by the late Ruth Stephens Gani. #ShineDome22 UQ News

Another first prize from our group. Karla Prada Karla Prada winning the best presentation prize at QCVRN & Heart Foundation Research Showcase yesterday. Big congrats, Karla. Proud of you Queensland Cardiovascular Research Network Heart Foundation Griffith University QMNC AIBN Research #theranostics #thrombosis

I couldn’t be more thrilled to share one of the main research papers from my PhD is out! We present a novel nanoparticle with promising theranostic (simultaneous diagnosis and treatment) of thrombosis. Thanks to everyone who made this possible. doi.org/10.1002/smll.2…

How it started // How it's going doi.org/10.1038/s42003… Chris Wallace 🇪🇺 🏳️‍🌈