New nature A mechanism for why durable weight loss is so difficult: epigenetic memory of fat cells nature.com/articles/s4158… Ferdinand von Meyenn Laura Hinte

New in nature🧬: We discovered why keeping weight off is so challenging - fat cells retain an epigenetic #memory of their previous state, even after weight loss. This helps explain the biology behind weight regain. Excited to share our newest work! nature.com/articles/s4158…

Great collaborative work with Laura Hinte and Daniel Castellano from vonmeyennlab is out now!

Congrats to Laura Hinte + Daniel Castellano from the vonmeyennlab for their publication in Nature! We are proud to have contributed to the #sequencing effort. Special shout-out also to our bioinformaticians who were directly involved with this work, Adhideb Ghosh and Falko J. Noé

Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity go.nature.com/4i0IBDy

Now Online: Fat cells have long-lasting (epigenetic) memory go.nature.com/3Zwhlpf

New content online: Memory of obesity stored in adipocytes go.nature.com/3ZmlfzG

By characterizing adipose tissue cell types and transcriptional programs in health and disease the authors provide a roadmap for more phenotype-tailored options in obesity treatment. Cell Metabolism cell.com/cell-metabolis…

We are excited to present the first single nuclei atlas of metabolically healthy obesity in subcutaneous and visceral adipose tissue! Christian Wolfrum #obesity #metabolichealth #adiposetissue

Unveiling adipose populations linked to metabolic health in obesity "Researchers generated a comprehensive cellular map of subcutaneous and visceral AT of individuals with metabolically healthy and unhealthy obesity.…" Open Access cell.com/cell-metabolis…

ETH VP Christian Wolfrum highlights the importance of #Medical #Research for unresolved clinical issues and explores enhancing collaboration between ETH and hospitals, along with plans to consolidate medical research activities. brnw.ch/21wQsej

Forschende erstellten einen detaillierten Atlas über Veränderungen in Zellen von übergewichtigen Menschen. Er könnte ausserdem Unterschiede bei der Entstehung von Stoffwechselerkrankungen zwischen Männern und Frauen erklären. brnw.ch/21wQubi

Our collaborative research from Christian Wolfrum investigating why some individuals with obesity stay metabolically healthy! #obesity #metabolichealth #adiposetissue #insulinresistance #insulinsensitivity #singlecellomics

Great resource for the adipose community! Check it out!

On this #WorldObesityDay, we bring you this Special Issue on Obesity, highlighting the complexities of this disease and systemic challenges we must overcome to combat it. cell.com/cell-metabolis…

Check out the roadmap to the first consensus atlas of human and mouse #adiposetissue. Great initiative by the adipose bionetwork of Human Cell Atlas!

🚀 Kicking off this first day of #GenomicMechanisms25 with Daphne Koller founder and CEO of insitro 🗣️ Machine Learning for Better Medicines #science #Genome #Drug Novo Nordisk Foundation Center for Genomic Mechanisms Disease at Broad Institute

REVIEW | Anne Loft, MP Emont, E Rosen et al. (Department of Biochemistry and Molecular Biology, The University of Chicago, Harvard Medical School): A roadmap towards achieving consensus on #singlecell transcriptomics data in #adipose tissue. FREE TO READ: nature.com/articles/s4225…

REVIEW | Anne Loft, MP Emont, E Rosen et al. (Department of Biochemistry and Molecular Biology, The University of Chicago, Harvard Medical School): A roadmap towards achieving consensus on #singlecell transcriptomics data in #adipose tissue. FREE TO READ: nature.com/articles/s4225…

Do check out the #epigenome atlas of mouse #adipocytes!