Happy to share our newest preprint on #tcells in type 1 #diabetes 👩‍🔬. Thanks for the excellent collaboration Ondrej Stepanek - Lab of Adaptive Immunity Institute of Molecular Genetics and Fakultní nemocnice v Motole 2. lékařská fakulta Univerzity Karlovy Vít Neuman! Surprisingly, T cells in T1D including #Tregs were biased towards naive phenotypes: biorxiv.org/content/10.110…

Indeed. MŠMT Marek Ženíšek

🧠Is your brain ready for PhD? Learn more about our projects 👉img.cas.cz/phd Join us, we are waiting for you! Your future starts now! #phd #phdstudent #science #openpositions #phdcommunity #prague 📸Mitra Tavakoli

Consequences of the Open Access religion.

Thank you for this official update. Our project ActSwiftly started on January 1, 2025. We are working hard to understand T-cell fate choices in adaptive immune responses.

We have one open PhD student position in the lab this year.

💗Join Eva in the Laboratory of Ondrej Stepanek - Lab of Adaptive Immunity Learn more about our PhD projects 👉img.cas.cz/phd Join us, we are waiting for you! Your future starts now! #phd #phdstudent #science #openpositions #phdcommunity #prague

Happy to present our story on how #actin and #CDC42 regulate #ectocytosis and #ciliaryvesicle shedding in #BardetBiedlSyndrome at 30th Cytoskeletal Club in Liblice🌞

Check out our fresh review on converging mechanisms controlling #cilia dynamics during #cellcycle and #signaling. With Čajánek lab we explored the dual roles of cilia factors and cilium turnover during specific cell fates and cancer. Many more here rdcu.be/epVDc Enjoy🙂

This is an interesting study. It would be even more impactful if it included the analysis of T-cell clones by scTCRseq to monitor how the clonal families change their phenotype over time.

Latest pre-print from our lab presents Experimental autoimmune adrenalitis - the first defined mouse model of Addison's disease. It reveals a key role of IFNg produced by self-reactive CD4+ T cells in the autoimmune pathology. biorxiv.org/content/10.110…

RIP GAČR :(

Vědní rozpočet na letošní rok je 43.3 miliard. RVVI na rok 2026 navrhla 46.8 miliard, MF teď navrhuje 43.5 miliard, což je nárůst o 0.5% oproti letošku. Meziroční inflace bude letos okolo 2.5% 🤦‍♂️ #takdekujem #tahlezemeneniprovedce

denikreferendum.cz/clanek/237843-…

Happy to share our latest preprint. We revisited the role of LCK in cytotoxic T cells. LCK-deficient T cells showed limited proliferation in vivo, but unexpectedly enhanced effector T-cell formation. biorxiv.org/content/10.110…

Congratulation to all grantees! 4 grants to CZ is ok, but not impressive. 1 in life sciences is too few. 0 for Akademie věd ČR is a failure.

Já bych dokonce řekl, že takto se ta dobrá, natož excelentní :), věda dělat nedá. Bez toho "skoro".

Conditional generation of real antigen-specific T cell receptor sequences Nature Machine Intelligence UNC-Chapel Hill 🇺🇸 nature.com/articles/s4225…