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…and we’re back!! 🎉 Following the unfortunate loss of our previous account, you can now follow the group on this one, or Andy himself Andrew Smith 🧪

Check out some gorgeous chemistry from Tengfei and Justin!

Check out Ding’s recent work investigating divergent substrate reactivity in conjugate additions, with some beautiful computational insights from Ali Goodfellow 💻🧪 pubs.rsc.org/en/content/art…

Congratulations to Dr Zhuan Duan for passing his viva today! 🎉 Thanks to Dr James Taylor and Iain Smellie for a great chat about kinetics and NHCs!🧪 Check out Zhuan’s recent work at pubs.rsc.org/en/content/art…

Great work by Aífe and the team!

The second group preprint of the week! Super work by Shubham Agrawal Dr Raj Kumar Tak Ali Goodfellow Andrew Smith Enantioselective Synthesis of Tetra-substituted 3-hydroxyphthalide Esters by Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution - go.shr.lc/47R7Xxq

The third group preprint of the week! Great chemistry by Haoxiang and Alejandro as well as comp insight all the way from Oregon! Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution of Tetra-substituted Morpholinone and Benzoxazinine Lactols - go.shr.lc/48RoX8f

Interested in mechanism? Enantioselective [1,2]-Rearrangement of Allylic Ammonium Ylides ChemRxiv go.shr.lc/4870evn. Huge team effort led by Will Hartley Mark Greenhalgh and Kevin, @belab.bsky.social St Andrews School of Chemistry and computational expertise from the Cheong Group Oregon State University

Congrats to the king of scale up! You’ll be sorely missed in the lab but good luck for everything 👨‍🚒

Great to see this work out- congrats to all the team! doi.org/10.1002/anie.2…

…and another one! Congrats to all the team! doi.org/10.1002/anie.2…

Synthesis of Tetra-Substituted 3-Hydroxyphthalide Esters by Isothiourea-Catalysed Acylative Dynamic Kinetic Resolution (Andrew D. Smith and co-workers) Andrew Smith Shubham Agrawal Ali Goodfellow St Andrews School of Chemistry #openaccess onlinelibrary.wiley.com/doi/10.1002/an…

Join us this week as Shubham Agrawal Andrew Smith shares his recently published work on isothiourea catalyzed dynamic kinetic resolutions!! Thanks to Reem for hosting! Link: youtu.be/Y4zJ7cUO3ds Angewandte Chemie Int. Ed. 2024, 63, e202402909. doi.org/10.1002/anie.2…

I recently had the opportunity to present my work on Isothiourea -catalysed DKR on the Synthesis Workshop YouTube channel. Watch to explore this unique approach to a challenging DKR. youtu.be/Y4zJ7cUO3ds?si… Andrew Smith ADS Group #research #OrgChem #Chemistry

Really pleased to see this manuscript out John Callahan - our longest running and most complex project to date! Congratulations especially to Will Hartley Mark Greenhalgh and Kevin plus the rest of the team including Cheong group Oregon State University. pubs.acs.org/doi/10.1021/ja…

Great to see this work out - congratulations to Martha and the team! onlinelibrary.wiley.com/doi/10.1002/an…

Great to see this work out - congrats to Ffion and Yihong! pubs.rsc.org/en/content/art…

Isoselenourea-Catalyzed Enantioselective Pyrazolo-Heterocycle Synthesis Enabled by Self-Correcting Amide and Ester Acylation (Andrew D. Smith and co-workers) ADS Group St Andrews X-ray Crystallography St Andrews School of Chemistry #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/an…

We had a great week at the 26th Lakeland Symposium in Grasmere! We’ve heard some phenomenal science, seen some beautiful scenery, and learnt that Andy has a very different idea of a gentle walk to the rest of us! 🧪🏞️ #RSCGrasmere #HeterocyclicChemistry