"There isn’t an ID doc in this country who hasn’t been at the bedside of a patient who’s desperately ill & for whom we did not have an antibiotic.” IDSA President Dr. Cynthia Sears. #IDquotes #IDTwitter Retweet if you ever had a patient with no #antibiotic to treat.

For pharyngotonsillitis (eight reviews, of which six did a meta-analysis), sufficient evidence exists to support short-course cephalosporin but not short-course penicillin when dosed three times a day #idxposts

For sinusitis the evidence appears to support a shorter regimen, but more evidence is needed in the population who actually require antibiotic treatment. #idxposts

Super interesting ⚡️⚡️ Evaluation of Etest and MICRONAUT-AM Assay for Antifungal Susceptibility Testing of Candida auris: Underestimation of Fluconazole Resistance by MICRONAUT-AM and Overestimation of Amphotericin B Resistance by Etest #idxposts mdpi.com/2079-6382/13/9…

Do you think there should be an alternative, more humble and equitable approach to developing clinical guidelines?

"We provide prospectively collected real-world evidence supporting the feasibility and safety of partial oral treatment for infective endocarditis, emphasizing the importance of careful patient selection..." #endocarditis #oralantibiotics #CMICommunications #OpenAccess

In the subanalysis, patients who received AGs in combination with CAZ/AVI had a 67.9% lower odds of 30d mortality compared to those that received only empiric AGs (no overlap with ceftazidime/avi), which may be a clinically meaningful reduction and trended toward significance

Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 I am in favor of reconsidering all aspects of Abx prophylaxis for cirrhosis. Studies have generally been small and with methodological limitations. The strength of recommendations are not supported by the quality of data.

🆕️🔥Systematic review & meta-analysis Inhaled antibiotics hold promise for mitigating the risk of VAP among critically ill patients. However, their impact on mortality, length of stay in ICU and hospital, and MV duration was not statistically significant sciencedirect.com/science/articl…

The receipt of an aminoglycoside in combination with ceftazidime/avibactam was associated with a higher odds of in-hospital mortality, possibly due to increased severity of illness in patients receiving aminoglycosides #idxposts

🆕️⚡️⚡️Retrospective Study #AAC Real world data Incidence of serotonin syndrome in patients receiving tedizolid and concomitant serotonergic agents #IDXpost Linezolid vs. Tedizolid? journals.asm.org/doi/10.1128/aa…