James Sleigh
@j_n_slayer
@The_MRC-funded group leader at @UCLIoN studying peripheral nerve diseases to develop targeted gene therapies #CMT #ALS #SMA #AxonalTransport | he/him
ID: 3617256795
http://sleighlab.com 11-09-2015 05:50:16
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Simply superb study from Sunaina Surana identifying critical co-receptors for tetanus toxin entry into neurons UCL Queen Square Institute of Neurology UCL Brain Sciences UK Dementia Research Institute #NeuromuscularJunction #SignallingEndosome
👋Hi new followers! 👋 At Journal of Anatomy, we seek to advance the understanding of all aspects of human and comparative anatomy through the analysis of structure, function, development, and evolution. More about us, and submit your papers here: onlinelibrary.wiley.com/journal/146975…
Say hello to the newest mitochondrial protein, profilin 1 (if you don't read preprints)! We stepped WAY outside of our comfort zone to bring you this study, finally published today in EMBO Reports. Beyond proud of the whole team for making this happen. embopress.org/doi/full/10.10…
Very excited to see our latest work on how BK channel gain-of-function mutations disrupt movement published in Current Biology today. cell.com/current-biolog…
REGISTRATION IS OPEN!!! nico.ottolenghi.unito.it/Agenda/8-9-Nov… Marina Boido NewroNico Brain Development and Disease group
Happy to share our paper on long-term single-particle tracking in live neurons Nature Chemical Biology. We showed that the number of active dynein motors can switch stochastically during the long transport, and we resolved the molecular steps of dynein. nature.com/articles/s4158…
Very nice work combining strategies for AAV targeting to muscle from Annalucia Darbey of the FrattaLab: biorxiv.org/content/10.110… UCL Queen Square Institute of Neurology UCL Brain Sciences The Crick UCL Div of Surgery UK Dementia Research Institute
Delighted to share our new paper in @BrainComms: Timing of SMN replacement therapies in mouse models of spinal muscular atrophy: a systematic review and meta-analysis academic.oup.com/braincomms/art…
Muscles 💪 and AAV 🦠 - what more could you ask for? Our preprint highlighting strategies for effective transduction of skeletal muscle with AAV with Wenanlan James Sleigh FrattaLab : biorxiv.org/content/10.110… UCL Queen Square Institute of Neurology UCL Brain Sciences UCL Div of Surgery The Crick UK Dementia Research Institute
In this interview, we talk to Alessio Vagnoni about his research investigating intracellular trafficking and a recent study that found different areas of neurons age differently >>> biotechniques.com/neuroscience/h…
Fantastic episode of Dr Rupy Aujla with Stuart Grice of FitnessGenes If you fancy a really interesting journey through genomics and personalised nutrition, as well as some great basic lessons on genetics, it's well worth a listen: thedoctorskitchen.com/podcasts/264-h…