📑 Common variable immunodeficiency disorder-related liver disease is common and results in portal hypertension and an increased risk of death
#LiverTwitter #OpenAccess

journals.lww.com/hepcomm/fullte…

📑 Adenine derivative acyclic nucleotide analogs (ADV, TDF and TAF), potentially bind to the ATP-binding site of growth factor receptors and inhibit their autophosphorylation, which might reduce the risk of #HCC ❕
#LiverTwitter

journals.lww.com/hepcomm/fullte…

📑 Incidence, clinical characteristics, and risk factors associated with recurrent #alcohol -associated hepatitis (rAH)

🚨 rAH developed in approximately 1 in 10 AH survivors and associated with 📉 long-term survival
#LiverTwitter #OpenAccess
journals.lww.com/hepcomm/fullte…

📑 Patients with #HBV -ACLF have a highly dynamic clinical trajectory and evolution of organ failures follows a specific pattern

💥A multi-state model enables the prediction of both #ACLF transition and outcome
#LiverTwitter
journals.lww.com/hepcomm/fullte…

There is no stepwise increase in the risk of encephalopathy with worsening psychometric scores in this international study

journals.lww.com/hepcomm/fullte…

Hepatology Communications Simon J. Gairing Patty Pringle Bloom, M.D. CLabenz

Does MRI screening improve survival for people with PSC?

journals.lww.com/hepcomm/fullte… #livertwitter

#LiverTwitter

Great study in Hepatology Communications showing
🏠💪 Home Exercise
💊 BCAA: branched-chain amino acids
🦠 Probiotica

✅benefit #Cirrhosis patients by decreasing
- 👋🦵 risk of falls
- 🏥🚑 ER room visits

this paper - written by a huge cast of all-stars - is a guide for action. Towards improving liver care for all

journals.lww.com/hepcomm/fullte…

Summarizes an AASLD conference proceedings

📑 Are there responders and non-responders to beta-blockers⁉️

This systematic review shows:
1️⃣ Homogeneous patient-by-patient response and
2️⃣ suggests routine portal pressure measurements may not be needed to guide beta-blocker use❕
#LiverTwitter

journals.lww.com/hepcomm/fullte…

📑 Intrahepatic neutrophil accumulation and extracellular trap formation are associated with posthepatectomy liver failure

💥Inhibiting NETs accelerates liver regeneration! Could this be a game-changer for post-hepatectomy liver failure⁉️
#LiverTwitter

journals.lww.com/hepcomm/fullte…

In recognition of #HepatitisAwarenessMonth , view the special #HepatitisElimination collection featuring articles from HEPATOLOGY Journal Liver Transplantation Journal (LTxJournal) Hepatology Communications ClinicalLiverDisease. journals.lww.com/aasldpubs/page… #LiverTwitter CDC Hepatitis

Great idea for patients in need of them

Unfortunately, though safe, this trial of an antibody against vascular adhesion protein - 1 was not able to reduce liver enzymes for patients with primary sclerosing cholangitis

doi.org/10.1097/hc9.00…

Important trial alert

Nina Kimer with ANOTHER huge trial in #cirrhosis care

Post-discharge intervention (home visits, phone calls, education) did not improve readmissions, survival, or quality of life - but some bright spots in secondary outcomes

journals.lww.com/hepcomm/fullte…

Liver transplant is a form a gene therapy for some rare inherited conditions

Today in Hepatology Communications, we report on the promise of gene editing and cellular therapy for Hereditary Tyrosinemia in mice. The cells were injected into the spleen

journals.lww.com/hepcomm/fullte…
#livertwitter

By the way, this is the ICD-10 code we recommended in this delphi process from last year in Hepatology Communications
ncbi.nlm.nih.gov/pmc/articles/P…

📑 LPAR1 antagonist, EPGN2154, improves liver #fibrosis and enzymes in preclinical #NASH 🐭 🐁
#LiverTwitter #OpenAccess

journals.lww.com/hepcomm/fullte…

📑 An online 💻📱mind-body intervention ⬆ mental health and quality of life in #PBC 🧘 
 
⭐️Those who took part >3x per week also had ⬇ fatigue!
#LiverTwitter #OpenAccess

journals.lww.com/hepcomm/fullte…

📑 The #GAAD algorithm is an in vitro diagnostic combining PIVKA-II and AFP, age and sex at birth, that significantly ⬆️ #HCC detection irrespective of disease stage, etiology or 🌍 region❕
#LiverTwitter

journals.lww.com/hepcomm/fullte…

📑 Smartphone 📱 sensors can serve as markers for alcohol craving & mood⁉️

💥 This study establishes feasibility of sensors for monitoring & prediction in #ALD -AUD❕
#DigitalPhenotyping #OpenAccess #LiverTwitter

journals.lww.com/hepcomm/fullte…

We issued the first retraction in Hepatology Communications history last week

It is being processed by the publisher

But I thought I would share some thoughts