Why don’t elephants get cancer?

(They do, but less often than humans)

Our latest YouTube video is live!

youtu.be/HbPpfD0yiZg?si…

Why don't elephants get cancer?

Our latest episode is up on YouTube. Give it a look and prescribe for future episodes.

youtube.com/watch?v=HbPpfD…

Our latest episode - 'Tusks & Tumor Suppressers' - is live!

We tackle why elephants are relatively protected from cancer compared to most other animals, despite their huge size. Extra p53, anyone?

podcasts.apple.com/us/podcast/89-…

open.spotify.com/episode/5F2UiF…

Friday mocktails featuring root beer floats 🍨🍨courtesy of our super star ⭐️ patient safety resident Sophia Mercadante Zara Latif, MD Eméfah C. Loccoh, MD Laura Burns Amin, MD Ayelet Shapira-Daniels Tony Breu

The patient is admitted and on IV Lasix BID for heart failure.

Initial K 3.7, Mg 2

Do you check BID lytes?

Enjoying outdoor lunch on a beautiful day in West Roxbury! Eméfah C. Loccoh, MD @ZaralatifMD Laura Burns Amin, MD VA Joint Chiefs. Missing hardworking attending Ayelet Shapira-Daniels.

Looking to learn a little physiology and medicine this Sunday morning?

Grab some ☕️ and read our latest episode's show notes about why pulmonary vasodilators can worsen hypoxemia w/ COPD-associated pulmonary hypertension.

open.substack.com/pub/thecurious…

curiousclinicians.com/2024/05/01/epi…

Hold your breath for this one! On our latest episode, The Curious Clinicians answer a puzzling pulmonary physiology question: Why can systemic pulmonary vasodilators worsen hypoxemia in COPD-associated pulmonary hypertension?

podcasts.apple.com/us/podcast/88-…

open.spotify.com/episode/0SJM2V…

1/14
What is the mechanism of night sweats?

We ask about 'fevers, chills, and NIGHT sweats', not 'fevers, chills, and DAY sweats.' Why?

To understand the answer, we'll need to cover temperature regulation, circadian rhythms, and more...

1/18
🤔Why does heart failure with preserved ejection fraction (HFpEF) lead to sodium retention?

With reduced ejection fraction (HFrEF), decreased cardiac output (CO) leads to neurohormonal activation and sodium avidity.

If CO is preserved in HFpEF, what's the inciting event?

1/
Why do patients with hyperbilirubinemia become jaundiced? Patients with hemochromatosis don’t get “scleral bronze”. Why does bilirubin “do' what it does?

The answers will require review of an article written 90 years ago, in German…

Don’t miss our first video podcast on YouTube!

Why do your fingers wrinkle in the bath?

youtu.be/V5cL_hd26JU?si…

Hannah, Avi, and I are very excited to announce our new Curious Clinicians YouTube page. Check out our first video and subscribe to see what we have in store!

youtube.com/channel/UCnhM2…

Things We Do for No Reason™: Routine respiratory pathogen panels for emergency department and hospitalized patients …mpublications.onlinelibrary.wiley.com/doi/full/10.10…

1/10
Does epinephrine improve outcomes in patients with cardiac arrest?

This is a question with a complex answer. This thread is only meant to scratch the surface and is a follow-up to a recent tweetorial on the use of epinephrine for cardiac arrest.

Tony Breu If you have an intervention that increases ROSC/survival but does not simultaneously protect the brain, then you will get more survivors with both good & bad neurological outcome with ratios likely dependent on median ROSC time. You would likely find the same for CPR/defib (1/n)

1/17
🤔Why do we use epinephrine to treat cardiac arrest?

Epinephrine can CAUSE cardiac arrest. And yet we give it as part of ACLS to treat the condition it caused.

This paradox requires explanation.

📣 Cool announcement! 📣

We have officially launched the The Curious Clinicians YouTube channel!

First episode answers the question, why do your fingers wrinkle in the bath?

youtu.be/V5cL_hd26JU?si…

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Why hasn’t group A strep (GAS) developed resistance to penicillin?

This is particularly odd given that other closely related gram-positive species (e.g., Strep pneumoniae) have resistant strains.

Given the global burden of disease, understanding GAS is essential...

Why do your fingers wrinkle when you take a bath?

Find out the answer on our latest episode, ‘Aquagenic Wrinkling’!

curiousclinicians.com/2024/04/17/epi…

podcasts.apple.com/us/podcast/the…

open.spotify.com/episode/5CwLIg…