Scolaro et al. showed that cytidine deaminase (CDA) was upregulated in several immunotherapy-resistant tumors and contributed to the uridine diphosphate (UDP) pool in the extracellular milieu. bit.ly/4bS7GMC Tommaso Scolaro MartaManco CCB_VIB_KUL  Mazzone Lab

Just before the summer break! Very proud and excited to share our latest work on tumor macrophage ontogeny ! Spatial temporal regulation of TAM development revealed using time stamping approaches! Ms4a3 Creert2 is a gem! science.org/doi/10.1126/sc…, congratulations to the team!

News & Views by Anders Hofer How tumors hijack macrophages for immune evasion Pancreatic cancer cells are now shown to create a TME that protects them from immunotherapy by overexpression of cytidine deaminase.

nature.com/articles/s4301…

🔔ONLINE NOW! the Nature Cancer August issue! 🤩 Features: - #machinelearning models in #clinicaloncology - EGFR and PI3K inhibition to overcome adaptive resistance - effects of cancer cell nucleotide metabolism on immune #TME 👇 nature.com/natcancer/volu…

Time to read...check our paper out in the current issue of Nature Cancer 😎

Super happy to share that our paper is published in nature today! We've discovered how the breast is protected against tumor initiation—though it comes at a cost. 📰Read all about it here: bit.ly/3MSxoa1 🏥CCB_VIB_KUL Department of Oncology - KU Leuven The Netherlands Cancer Institute Van Rheenen Lab Benjamin Simons

Thrilled to share our first study on aging from Miriam Merad, MD, PhD lab Icahn School of Medicine at Mount Sinai The Tisch Cancer Institute Lipschultz Precision Immunology Institute in which we demonstrate how aging promotes cancer. We show that: (1/n) science.org/doi/10.1126/sc…

Glad to see our paper, among others, in this interesting collection about #CancerMetabolism and its impact on cancer research.🎉 Nature Cancer Springer Nature Take a look if you did not read it yet!👇

Ready for INCI2025-VIB on 7-9 May 2025 in Bruges😎 Submit your abstract (Deadline: 28th February)! Do not miss Prof.Garg from KU Leuven. He will update us on how to unravel cancer immune niches to guide immunotherapy approaches! #INCI2025 👉vibbio.tech/INCI25 Cell Stress & Immunity (CSI) Lab

#INCI2025. 2 days left to the abstract deadline (28th Feb). Don’t forget to do it! We will listen to Prof. Guilliams talking about spatial analysis on hepatic niches. How can you miss it? 🤩 Join us! (7-9 May in Bruges)🇧🇪 👉Check it: vibbio.tech/INCI25 Martin Guilliams

📢Few hours before abstract submission... I've just done it! Do not miss this great opportunity! 😎 #INCI25 👉vibbio.tech/INCI25

📢#INCI25 is getting closer! Subscribe to it! Prof. Bart Lambrecht will show us the alveolar niche and how it is implicated in inflammation and cancer. Do not skip his talk! 😎 🗓️Early Bird deadline: 26th March 👉Check it: vibbio.tech/INCI25 bart lambrecht

📢#INCI25: -1 day to the Early Bird deadline! Join us! Prof. Ken Lau will dig into the pre-cancer states focusing on the immune microenvironment. 🔔Time is running, do not miss this conference in beautiful Bruges!🇧🇪 Ken Lau Lab 👉Check it: vibbio.tech/INCI25

🔊Hurry up! There are only a few hours left to take advantage of the early bird rate at #INCI25. You don’t want to miss this game-changing conference in medieval Bruges. Spots are filling up fast, so register here: vibbio.tech/41KPm6h. #CancerBiology #Immunotherapy

Happy to share our latest reflections Trends in Immunology on our favourite cells: IL-1b+ macrophages 🔥🔥🔥 Molecular, spatial, temporal, functional properties in cancer and beyond.. it's all in there from the awesome nicoletta caronni, Federica and Luca Frosio. cell.com/trends/immunol…

📢#INCI25: Final deadline is around the corner: 23rd April! Subscribe to this exciting conference in Bruges!🇧🇪 Prof. Gabriel Victora will show us the clonal and cellular dynamics of the antibody response. How can you miss it? Victora Lab 👉Check it: vibbio.tech/INCI25

📢#INCI25 Final deadline is tomorrow: 23rd April! Join us in Bruges! Don't miss this opportunity! We will listen to Prof. Laurence Zitvogel on cancer risk score and interceptive measures in cardiovascular disease patients. Gustave Roussy 👉Check it: vibbio.tech/INCI25

If you are curious how #CancerBiology and #Immunology are interconnected, now is your chance to participate in #INCI25. ⏳ Registration closes today! Don’t miss this great opportunity to learn from the best. There are just a few hours left: vibbio.tech/3GjKRY2. #Immunotherapy

Sustained Macrophage Reprogramming Is Required for CD8+ T cell–Dependent Long-Term Tumor Eradication brnw.ch/21wV0or GIMM Foundation NMorais Lab #gimmcare