The simultaneous activation of cytotoxic granule-mediated programmed cell death, apoptosis, and necroptosis cause widespread keratinocyte death in Stevens–Johnson syndrome and toxic epidermal necrolysis.
go.nature.com/3Qkfw9Q

Selected Flavonols Targeting Cell Death Pathways in Cancer Therapy: The Latest Achievements in Research on Apoptosis, Autophagy, Necroptosis, Pyroptosis, Ferroptosis, and Cuproptosis | MDPI
Nutrients mdpi.com/2756308 #mdpinutrients via Nutrients MDPI

Antileukemic potential of methylated indolequinone MAC681 through immunogenic necroptosis and PARP1 degradation dlvr.it/T6SBJK

Shamelessly dropping in from a long hiatus to plug our most recent preprint, in which we show a function for the necroptotic kinase RIPK3 in modulating neurotransmission (independently of necroptosis!).

Congrats to first author Irving Estevez!

biorxiv.org/content/10.110…

Antileukemic potential of methylated indolequinone MAC681 through immunogenic necroptosis and PARP1 degradation dlvr.it/T6Rwjv

Today I had the chance to meet one of the giants in the cell death field - Vishva Dixit! What a great opportunity to hear about the history (and future!) of apoptosis and necroptosis research.

Thanks Rapé Lab for organizing this event!

Buy UH15-38, the RIPK3 inhibitor featured in this Nature paper, here: bit.ly/4bseOjh

#RIPK3 #necroptosis #lung

Casein Kinase 1G2 Suppresses Necroptosis-Promoted Testis Aging by Inhibiting Receptor-Interacting Kinase 3 published as: dx.doi.org/10.7554/elife.… eLife - the journal #biorxiv

Immunogenic cell death in cancer: targeting necroptosis to induce antitumour immunity | Nature Reviews Cancer nature.com/articles/s4156…

🚨 $OTLC - OTCQB

🗞️ Press Release - Oncotelic Therapeutics, Inc. to Sell Its Necroptosis Cancer Therapy Assets to Mosaic ImmunoEngineering, Inc.

🔗 otcmarkets.com/stock/OTLC/new…

$CPMV - Mosaic ImmunoEngineering
🔹Agrees to Acquire Clinical Necroptosis Cancer Therapy Assets from Oncotelic Therapeutics, Inc.
🔹Very Low float/ OS near 7M shares

👆 0% PreM/ $0.31

nature.com/articles/s4156…

zedie.org/2024/05/04/imm…

Buy UH15-38, the RIPK3 inhibitor featured in this Nature paper, here: bit.ly/3UcC5yv

#RIPK3 #necroptosis #lung

Exciting news! $OTLC sells Necroptosis Cancer Therapy Assets to $CPMV! 🚀 The strategic move will boost Mosaic with clinical-stage assets and AI tech to advance cancer treatments. 💊🧬 #Biotech #CancerResearch #HealthcareInvesting #OTLC #CPMV 💪 #Stocks .

Edaravone Dexborneol mitigates pathology in animal and cell culture models of Alzheimer's disease by inhibiting neuroinflammation and neuronal necroptosis dlvr.it/T677yL

Oncotelic Therapeutics, Inc. to Sell Its Necroptosis Cancer Therapy Assets to Mosaic ImmunoEngineering, Inc. $OTLC healthstockshub.com/news/otcmkts/o…

Mosaic ImmunoEngineering Agrees to Acquire Clinical Necroptosis Cancer Therapy Assets from Oncotelic Therapeutics, Inc. $CPMV healthstockshub.com/news/otcmkts/c…

Drs. Avishekh Gautam, David Boyd, and colleagues at Fox Chase Cancer Center and St. Jude developed a method to prevent lung injury in #influenza by blocking #necroptosis ! 🫁

Read the nature paper: go.nature.com/43WgONR

Listen to the discussion: bit.ly/3JvTXiU

Dietary #curcumin alleviates intestinal damage induced by ochratoxin A in juvenile grass carp (Ctenopharyngodon idella): Necroptosis and inflammatory responses
sciencedirect.com/science/articl…