Diagnosis?

NEJM #MedEd #MedX

Parkinson's Disease is synonomyous with aging--most patients in 70s, 80s, 90s
Yet RCT of a new treatment for PD has an age cutoff of 75.
Seriously? How did this get through IRB?
Time to put a stop to Ageism in medical research
nejm.org/doi/full/10.10…

New NEJM Study Finds Pfizer’s PAXLOVID Does ‘Little Or Nothing’ For COVID-19!

Is anaerobic coverage necessary for aspiration pneumonia with metronidazole or Augmentin?
NEJM JWatch reports from a large retro study with N ~ 4000

Findings show no added mortality benefit but an increased risk of CDI

journal.chestnet.org/article/S0012-…

#IDTwitter #IDXposts

The entire results of the #ENRICHtrial have been published in NEJM.

The main takeaway? MIPS improved safety, functional, and economic outcomes in intracerebral hemorrhage for appropriate patients.

See for yourself: bit.ly/3vDMJ9r

How is it possible that a study on TAVR vs SAVR in low risk patients gets published in the NEJM with equivalence at one year? Who cares about one year in low risk patients? #falsenews NEJM Mass General Heart

There's never been a disease-modifying drug for Parkinson's disease to slow its progression. Now there may be two emerging.
—GLP-1
nejm.org/doi/abs/10.105… NEJM
—anti-synuclein antibody nature.com/articles/s4159…
NATURE.med

Routine beta blockade for acute MI when EF is preserved? Standing in stark contrast to historic pre-PCI era beta blocker trials, this landmark trial showed NO outcomes difference — calling into question other “accepted” practices in the modern era. REDUCE-AMI Trial, NEJM 2024 ♥️

In the ENRICH trial of minimally invasive cerebral hematoma removal within 24 hours after onset of hemorrhage, functional outcomes were better with surgery than with medical treatment, particularly among patients with lobar hemorrhages. Full trial results: nej.md/3VPYggf

Michael Mina CDC Mandy K. Cohen, MD, MPH NEJM It's not the clearest high res, but it'll do ...

Swapnil Hiremath @[email protected] DOPPS So, I guess you're not CONVINCEd

Effect of Hemodiafiltration or Hemodialysis on Mortality in Kidney Failure ca. 2023 from NEJM
#Nephpearls #ISNWCN 🇦🇷

👉 pubmed.ncbi.nlm.nih.gov/37966299/

Science behind the Study: CAR T-Cell Therapy for Glioblastoma nej.md/49yGoKf

#Neurology

DOACs for rheumatic atrial fibrillation? This trial showed INCREASED mortality and stroke/thromboembolism when compared to warfarin, our standard of care. A trial in support of current guidelines for vitamin K antagonism in this population. INVICTUS Trial, NEJM 2022 ♥️

Karen Strine Eric Topol NEJM NATURE.med Specifically this post: absolutelymaybe.plos.org/2024/03/29/a-h…

K-12 School Shooting Database The leading cause of child and adolescent deaths is motor vehicle crashes.

Stop lying.

nejm.org/doi/full/10.10…

先日のNEJMのアレクチニブ術後補助療法について、論文を分かりやすくまとめました✍️

🚨 New NEJM Study Finds Pfizer’s Paxlovid Does ‘Little or Nothing’ for COVID-19

“Kind of shocking a drug that costs $1,300…is showing in a randomized controlled trial to not really relieve COVID symptoms.

Erin Elizabeth Health Nut News 🙌 This is how money laundering works via the NEJM and the pharma corporations.

The NEJM will claim it is independent, but only after billions of dollars were spent by 'governments' on a failed and dangerous drug.

Job done. Same authors. Different conclusion.
#NEJMgate again

The fact that there has not been a single article in the NEJM on this war — a war where bombed hospitals and now famine are center stage! —  is utterly indefensible. Everyone will agree on this in some years to come, when it's too late to alter the course of events.