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What a joy, the first #SaxoCell consortium meeting took place at the CRTD in Dresden yesterday. Thanks to our members for numerous interesting presentations and fruitful discussions! #C4F #ZellundGentherapie CRTD TU Dresden Fraunhofer IZI UNIVERSITÄT LEIPZIG

I can highly recommend Georg as a supervisor and mentor. Go for it!

Wir freuen uns auf Montag!

💡Exciting Emerging Science 1. In-vivo CART / reprogramming 2. Full gene knock-in 3. Non-viral GTx 4. AID - TReg biology 5. RNA Editing 6. Epigenetic editing 7. Fibrosis 8 Tech to limit Off Target Editing 9. miRNA to modulate RNA expression 10. Nucleic acid immune modulators

More efficient CRISPR. 🤝 Cas9 fused to PRDM9, a protein that methylates histones, increases homology-directed repair three-fold. No increase in off-target editing. Works in multiple cell lines. So simple. Is there anything that can't be fused to Cas9? pnas.org/doi/10.1073/pn…

Proud to be elected as the best graduate of my faculty Biotechnology Center (BIOTEC) of TU Dresden. Thanks for creating such an intriguing Molecular Bioengineering master's course!

.Lukas T. Schmitt Buchholz Lab report Recombinase Generator, RecGen, an algorithm for generation of designer-recombinases go.nature.com/3XrRWsV

Bacteria that use histones to organize their chromatin. There. I said it. biorxiv.org/content/10.110…

Thanks to our incredible #SeriesB funders, we're thrilled to announce the launch of our new Avian Genomics Group, whose first undertaking will be the de-extinction of the iconic #dodo 🦤 bird. #itiscolossal Rediscover the dodo: colossal.com/dodo

We´re hiring! Werde Teil unseres #SaxoCell Teams im Bereich #Technologietransfer und hilf uns dabei Sachsen zu einem Zell- und Gentherapie-Hotspot zu machen! bit.ly/3JUb67j #wearehiring #celltherapy #genetherapy #bmbf #clusters4future

Am 14. März erscheint die neue #Podcast-Folge You Ask – We Explain der @DHMDresden und weiteren Partnern zum Thema „Von Genen und Menschen – wer wir sind und was wir sind“ mit #SaxoCell-Mitglied Frank Buchholz und weiteren Expert:innen! Hört gern rein!

Buchholz Lab new manuscript alert! 🚨 This time with me as a first author! 🥳 Read the thread bellow for a short summary of the work! 🧵 academic.oup.com/nar/advance-ar…

Our Nature Biotechnology Research Briefing article is now available! Get a quick summary of our research and gain insights into what was behind the paper. #genomeediting #recombinases #zincfinger

Buchholz Lab @Medizin_TUD TU Dresden Liliya Mukhametzyanova Groundbreaking genome editing tools unlock new possibilities for precision medicine #NBTintheNews via TU Dresden tu-dresden.de/med/mf/die-fak…

Check out our 3 #SaxoCell members Paul Warncke from Klinikum Chemnitz, Pascal Schönberg from TU Dresden and @IlkaHenze from Fraunhofer IZI IZI being portrayed by the #Faces of SPIN campaign from #SPIN2030! spin2030.com

New faces in the Buchholz Lab! Welcome with us: Anandh Anandh Ravishankar, our new bioinformatics expert 🖥️, Conal, our new Recombinase wizard 🪄 and Pascal, our new Base Editing Maestro ✂️🧬

Gorgeous from Jamie Hackett: "Nevertheless, we did observe striking interactions between specific marks and cis genetics" Fellow epigenome editors - we long suspected this could be the case. Now we know. This will be a wild - and essential - ride. nature.com/articles/s4158…

I‘m happy to finally share my first (shared) first author paper, which originated from the work of my master thesis. We engineered a food microbe to produce hops flavor - Cheers! 🍺 pubs.acs.org/doi/10.1021/ac…

I’m happy to share our new publication!🎉 We explored the regulatory elements driving constitutive T cell receptor expression by leveraging CRISPR-based screening. A big thank you to all collaborators! frontiersin.org/journals/immun… TU Dresden CRTD HZDR @[email protected]