Really looking forward to this!

Thank you FocalPlane for shortlisting my image of neuromuscular junctions in your competition. Please vote for number 5 - it could be on the cover of Journal of Cell Science!🔬👩🏻‍🔬 focalplane.biologists.com/2023/07/04/foc…

Transcriptome-wide RNA binding analysis of C9orf72 poly(PR) dipeptides, delighted for this work with Adrian Isaacs, Rubika Balendra, PataniLab, ule_lab et al. to be out in LifeScienceAlliance! life-science-alliance.org/content/6/9/e2…

Check out our new preprint on generation and characterisation of C9orf72 polyGR and polyPR knock-in mice. A huge effort over many years by Carmelo Milioto and many collaborators incl. Marc Aurel Busche Soyon Hong biorxiv.org/cgi/content/sh… 1/5

Well done Becca!!

Happy to share our latest paper: "A scalable human iPSC-based neuromuscular disease model on suspended biobased elastomer nanofiber scaffolds" Co-authored with the fantastic Aimee Cheesbrough, Wenhui Song, published in Biofabrication IOP Publishing iopscience.iop.org/article/10.108…

Image 2 of 4: Eruption of Etna's Embers Human neurons grow in a device (bottom), and the 'wires', which carry the electrical impulses, travel through tiny grooves to get to the other side (top). This chaotic network of the wires gives the effect of a volcanic eruption. 4/6

The first of the 2023 Brain Prize webinars is THIS WEEK- 25th October 4-6pm CET. The 2023 winners Christine Holt, Michael Greenberg & Erin Schuman will present their prize-winning research. Free and online. Register at lundbeckfonden.com/events

New BioRxiv paper on using cryptic splicing to unlock precision gene therapy activation for ALS, FTD & other TDP-opathies! Key contributions Max Z. Y. J. Chien Josette Wlaschin +many others from Claire Le Pichon ule_lab FrattaLab labs and more. A thread 🧵 1/13 biorxiv.org/content/10.110…

Delighted to see our study led by Carmelo Milioto revealing a neuroprotective ECM signature in C9FTD/ALS published! Thanks to MND Association UK Dementia Research Institute and many others! nature.com/articles/s4159…

Join us in Okinawa, Japan for an EMBO workshop on axon degeneration and regeneration this October. Child care and travel grants available. meetings.embo.org/event/24-axons

What a beautiful work! I might be biased as it contains all of my favourite things 🤩

NeuroBioUK is back for 2024! A one day meeting dedicated to all things neuronal cell biology. Submit your abstract by the 2nd of August to be considered for a talk. neurobiouk.sites.sheffield.ac.uk/contact Please help us spread the word! You can join the email list on our website.

Having seen this from the very beginning, @surana_sunaina you have been a superstar! Lots of cool experiments and overall great science! Well done 🎉

Of that time when breakfast with Elodie turned into a podcast episode about science, neurons and funky plants 👩‍🔬🔬🌱

Out Science Magazine! New tech to activate ALS gene therapies only in the right cells at the right time - Increased safety to have more options for ALS. We do it by taking advantage of cryptic splicing. science.org/doi/10.1126/sc… UCL Queen Square Institute of Neurology The Crick Oscar Wilkins Max Z. Y. J. Chien

Such a nice work! It’s been amazing to see this develop and how neatly, taking advantage of cryptic splicing, you can deliver gene therapy to neurons that have lost nuclear TDP-43. Well done Oscar Wilkins!

Heterogeneity of late #endosome/#lysosomes shown by multiplexed DNA-PAINT imaging. New quantitative pipeline developed by Charles Bond (Charlie Bond), Melike Lakadamyali (@Melike_Lak) and colleagues Penn Medicine: hubs.la/Q02WCKPJ0 #Biophysics #Organelles #Technology

My lab is looking to recruit PhD students starting in Fall 2025. We currently have two projects advertised (details for each below) aiming to understand the molecular regulation of mRNA capture and translation at the synapse Please reach out if interested! 1/3

🔬🧠 We're hiring!! Research associate opportunity @dsb_unipd Pennuto Lab Deadline: *10th January 2025* #MotorNeuronDiseases #LocalTranslation #SpatialOmics