More distraction: new #preprint we posted a little while ago biorxiv.org/content/10.110… looks at somatic copy number #evolution in #colorectal #cancer. Suggests a #CNA bottleneck adenoma->cancer, & thereafter CNAs experience #stabilising #selection, remarkably even in mets & chemo.

Clare is brilliant

[1/4] 🧬 Our phase I study of ATRi ceralasertib has been published (PATRIOT A,B). Long lasting responses, immune modualation and suggestion that inflamed tumours may do better? jci.org/articles/view/…

NEW REVIEW ARTICLE Nature Cancer – “Aneuploidy and complex genomic rearrangements in cancer evolution” by Peter Van Loo #TobyMBaker #SaraWaise #MaximeTarabichi. Read it here👇 nature.com/articles/s4301… rdcu.be/dxoLb

We're seeking advice from people who have experienced Head and Neck Cancer. If you are interested in helping us develop the new #ClinicalTrial, immunoREACH, you can join our discussion group. #PPI Find out more here: tinyurl.com/mjdyaztf Or email: [email protected]

Thank you to our consultant colleagues from around the UK who have voted in round 1 of our current Delphi on salvage surgery of the oral cavity/ oropharynx, and post-operative management of salvage surgical procedures. Round 2 will be opening this week!

Interested in meeting great people and hearing about their cancer research? Sign up for this years SETM symposium held at the Crick June 18th: eventbrite.co.uk/e/somatic-evol…

🎉👏 Congratulations to Dr Stephen-John Sammut (Stephen John Sammut) who has won the prestigious Graham Bull Prize from the Royal College of Physicians! The prize is in recognition of his work in personalised #BreastCancer medicine. Find out more 👇 icr.ac.uk/news-archive/i…

Multiple opportunities for CRUK Scotland Centre PhD studentship - Amazing projects, supervisors, environments! May 20 deadline Cancer Research UK in Scotland CRUK Scotland Inst UofG Cancer Sciences Institute of Genetics and Cancer Edinburgh Cancer Research Interested in computational modelling of gliomas? Get in touch! 👇findaphd.com/phds/project/f…

🆕 Breast cancer immunology paper out in Nature Immunology‼️⚠️ Buckle up for a deep dive into how our immune system fights breast cancer! 🥷💪🏻 Link to paper: rdcu.be/dGy70 #cancerresearch #bcsm #breastcancer Main messages, a 🧵: 👇🏻 OncoAlert

The lab’s first pre-print is out! ‘A microscopy reporter for cGAMP reveals rare cGAS activation following DNA damage, and a lack of correlation with micronuclear cGAS enrichment’ biorxiv.org/content/10.110…

Want to join our thriving Viral ImmunoTherapies & Advanced therapeutics Lab. lab, on a fully funded 🎉4 year 📷PhD? A Mowasi Scholarship available from Oct to develop molecular switches to control "smart viruses" to treat #Glioma #GBM #BrainCancer #DIPG #DMG please share/RT. findaphd.com/phds/project/d…

Ok it's tomorrow now 😬 - send speedy wishes and donations of any pennies all very welcome, will make sure it's well spent for cancer research, thank you!

In addition to being a TV and media star, it turns out Vin Paleri is really rather good at #hnscc surgery.

Recruiting a PhD student in computational cancer immunology! Surgery and Cancer Working on understanding the immune response to placental cancers: ~75% are cured with anti-PD1 therapy. Lots of cool questions to work on. findaphd.com/phds/project/m…

Does immune evasion matter for driver genes? Our latest work in Genome Biology with Maria Secrier Simon Walker-Samuel Andrea Sottoriva and the fantastic Lucie Gourmet explores how immune evasion impacts the driver landscape during tumor evolution. Check it out: bit.ly/4blmEul

It's not too late yet...but it almost is!! Check out this fabulous, fully funded, 4 year PhD project in my lab working on #DIPG #Glioblastoma #OncolyticViruses - you have till Sunday (30th) June at 5pm to apply!!! 👇👇👇👇👇👇👇👇

🚀 Excited to share our latest research! We developed GRITIC, a novel method for timing genomic gains using bulk WGS data. Our findings reveal non-parsimonious evolution and increased chromosomal instability post-genome doubling in tumors. aacrjournals.org/cancerdiscover… #cancergenomics

Inflammatory bowel disease (#IBD) increases bowel cancer risk: 1/3 of patients with low grade dysplasia (LGD) will get cancer. This risk is very high &reason for treatment. But also major conundrum b/c 2/3 patients with LGD won't get cancer. Can we know who is really at risk? 1/3

International Academy of Oral Oncology Liverpool Head & Neck Centre + BAHNO Head & Neck bringing an amazing World Congress to Liverpool in just 12 months time!!