This is the first chapter of a story about courageous patients and their families, of multidisciplinary teamwork, and hard-fought steps forward to effective therapy for #DIPG #DMG, a universally lethal cancer of the brain and spinal cord.🧵(1/) nature.com/articles/s4158…

1/ Alarm! There is a new #TrackMate extension, called the TrackMate-Helper, developed with the great @guijacquemet team. It helps finding automatically optimal tracking parameters, using the Cell-Tracking-Challenge metrics. A thread about what it does and why it is important

Hey #Microscopy Twitter I need major RT support! Daniel Stabley is recruiting a Lead Researcher to join his rocking core in the Developmental_Neuro department at St. Jude Research. You won't believe your 👀but Daniel's core has MOSAIC, LLSM & much more! Apply: careers-stjude.icims.com/jobs/9304/lead…

Please share the nerdiest joke you love

A very interesting perspective from Zlokovic lab on the work from our lab (Kipnis Lab) and the lab of Matthias Nahrendorf on how brain regulates its own immune response|| nature.com/articles/s4159…

Focal Plane meets ELMI 2022. Take part in an image contest and win a cover in the Journal of Cell Science! Open for all! focalplane.biologists.com/2022/05/09/elm… #ELMI2022 FocalPlane

Last day of #ASGCT22! Don’t forget to tune into Jorge’s talk “Dysfunctional Immune Synapses Restrain Anti DIPG Activity of CAR T Cells” in person or virtually at 11:30 EST room 206 St. Jude Research ASGCT #CARTcells #DIPG

How can mechanical force tell cytotoxic T cells where to target their killer cargo? We show how mechanically active integrin LFA-1 enhances cytotoxic power and fidelity. Check out our newest paper, which is now live Nature Communications! nature.com/articles/s4146…

Our paper is out!!! Thank you Nofar and Tamir for leading this work, and our collaborator Prof. Guy Ron, whom we converted from nuclear physics to cancer research! Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas cell.com/molecular-cell…

😍 Holy Moly! Ali H. Shaib just established ONE, a method combining #ExM and #SRRF to achieve one nanometre resolution imaging on most microscopes! Figures are beyond super!! Congratulations everyone, can't wait to try it

So proud of my daughter!

Sleep makes us nicer: worse sleep (both quantity and quality) reduces how much people help each other, including real-world altruistic acts), observable at 3 societal scales: within individuals, across individuals, and at a nationwide level. PLOS Biology journals.plos.org/plosbiology/ar…

Join this free ASCB webinar on Sept 28 to learn best practices on how to take great images, analyze them, and produce nice-looking figures. Presented by Stephen Royle Rhys Denver and moderated by Lorena Benedetti Sign up ➡️ ascb.org/ascb-meetings/…

The Haydar Lab Children's National Hospital 🏥 is recruiting! Join us to help treat childhood brain cancer. #Recruiting #postdocjobs #AcademicTwitter #Science cnhs.taleo.net/careersection/…

An amazing interview! I had the pleasure to be part of her lab, and, by far, one of the best experiences that I had. _______________ Muy buena entrevista! Tuve el placer de ser parte de su laboratorio, y por lejos, una de las mejores experiencias que he tenido.

An amazing meeting with outstanding people! SNO #SNO2022 Thank you so much for giving me the opportunity to talk about our work in optimizing CAR T therapy for DIPGs. @GiedreKrenciute St. Jude Research

The centrosome decides which branch extending from the body of microglia will successfully engulf and clear away dead neurons. elifesciences.org/articles/84659…

First corresponding paper is out! Thank you to Jorge and @GiedreKrenciute for the beautiful imaging and brain tumor models, Lindsay Talbot for the stunning HALO assay, and Stephen Gottschalk for the mentorship and support. All made possible by St. Jude and St. Jude Research

Join March 23, noon CT/1 pm ET, as Max Mamonkin of BCMHouston presents “CAR T-cells for T-cell Malignancies: Proving and Improving” and @GiedreKrenciute of St. Jude presents “What will it take to make CARTs effective for pediatric brain tumors?” bit.ly/SOCC23-TWORG #SOCC23