A new study finds that a previously overlooked type of immune cell, interstitial macrophage is the most susceptible cell to infection by SARS-CoV-2 that’s responsible for the critical transition from a merely bothersome COVID-19 case to a potentially deadly one! 1/

Are there any #neurologists who can see Hanna for an emergency appointment soon? She is in Birmingham, AL. She is suffering from frequent seizures, no hospital is accepting her, and her appt with her neuro is only in 2 weeks. Please help. #LongCovid #Neurology #Neuroscience

New, outstanding feature on #LongCovid and clinical trial efforts to address persistence of #SARSCoV2
science.org/content/articl…
Science Magazine J Couzin-Frankel

A must-read piece by Julia Marie dissecting 6 mainstreamed anti-vaxxer beliefs:

1: Viral & bacterial infections are good for the immune system

2: Public health measures & disease mitigation harms people

3: Public health shouldn’t pursue the elimination of pathogens

🧵/1

New: Airborne disease transmission risks on public transit buses: Impacts of ridership, duration, and mechanical filtration using a relative risk metric
sciencedirect.com/science/articl…

🧵 Is there hybrid immunity for measles like for COVID? If so, should that be a public health goal?

Answer from Dr Mansour Haeryfur, President, Canadian Society for Immunology

*Replying in a personal capacity, not on behalf of CSI or UWO

Have $5 bucks to spare? Every little bit extends my ability to continue what we started.

I hope for a day when Covid awareness is not needed, but we are not there yet, so I’m hoping you’ll help.

#Covid19   #LongCovid

gofund.me/00cdb2eb

A recent BBC news article about Long Covid tells of the experience of 2 patients. A short thread.

Dr Deepak Ravindran 'said he believed there were many people unknowingly living with the illness who are yet to recognise the symptoms.'

1/🧵

“Long COVID denialism puts you on the wrong side of history”
Apr 5 2024

H/T Felicity Nelson

🧵
Twitter.com/frogsandstars/…

#LongCovid
#LongCovid Kids
#TreatLongCovid
#PreventLongCovid
#ProtectNotInfect
#WeAllShareIndoorAir
#CleanAirNow

How SARS-CoV-2 replicates once it enters the cells, has made surprising discoveries that could be the foundation for future antiviral therapies. It also has important implications as replication of the SARS-CoV-2 has, so far, received less attention from researchers. 1/

Already gearing up for our ⁦ReSisters⁩ convo w ⁦Ziyad Al-Aly, MD⁩ next Wed April 10 at 8pm (Eastern). Lots to discuss regarding his expertise in epidemiology and his #LongCovid research. If there’s anyone who knows how to speak up, it’s Dr. Al-Aly! twitter.com/i/spaces/1rmGP…

Why SARS-CoV-2 elicits mild symptoms at first but then, for a subset of patients, turn potentially fatal a week or so after infection? A recent study showed that distinct stages of illness correspond with the coronavirus acting differently in 2 different populations of cells 1/

In a sample of 53 Covid survivors ~2 years post infection, cognitive impairment was associated with long-term alterations in the structure of the brain, visible on brain scan

#LongCovid
ajnr.org/content/early/…

APR 4 UPDATE: convergent evolution of JN.* Spike hits “level 4” (346+455+456+572I) with KW.1.1 and KZ.1.1.1

Yunlong Richard Cao Raj Rajnarayanan The Sato Lab (Kei Sato) Ben Murrell Etienne Simon-Loriere Eric Topol T. Ryan Gregory Ryan Hisner Marc Johnson Cornelius Roemer Federico Gueli 🏳️ Ben Murrell

I conducted preliminary phylogenetic analyses using H5N1 clade 2.3.4.4b genomes in North America with 2024 collection dates in GISAID. Here are some initial insights 1/7

“Congrats - you’re old! Maybe this year you will try and be normal again.”

This was a birthday message I received from a relative. They’re referring to my disabilities and to my Covid caution. They consider both “abnormal”.

🧵 on compassion, normalcy & chronic illness. /1

SARS-CoV-2 hit my salivary glands, gums & teeth hard. Was privileged to access >10 dental procedures over 4 years.

Think it’s helped clinically with my #LongCovid .

But the money I spent could have bought a luxury car.

Dental Care =Health Care

And should be covered for all.

New study reveals increased risk of allergic diseases after COVID-19 infection

“Researchers discovered that individuals infected with SARS-CoV-2 showed a 20% higher occurrence of allergic diseases compared to those not infected” news-medical.net/news/20240403/…

Convergent evolution has seen several SARS-CoV-2 sub-lineages of JN.1.* acquire the Spike F456L and R346T mutations aka 'FLiRT'.

The first chart shows the 9 leading countries by volume, the 2nd chart shows the next 9.
🧵

Hopeful claims w/o evidence: 'thanks to gained immunity reinfections pose minimal risk of #longCOVID '

Scientific evidence: studies that reported on reinfections & LC show that #longCOVID incidence follows (almost too well) the theoretical cumulative risk growth pattern.
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