We are delighted to announce that Professor Edith Heard has been appointed as our new director and chief executive! Edith, who is currently director-general at @EMBL, will succeed Paul Nurse in leading the Crick from the summer of 2025. 🔗 crick.ac.uk/news/2024-07-0…

Our teams is looking for a post-doc interested to study molecular conflicts between HIV/SIV and host antiviral factors (in a nice environment in Paris Institut Cochin)! euraxess.ec.europa.eu/jobs/253927#jo…

You are starting your PhD or a post-doctoral position in the field of neurodegeneration. You are interested in protein aggregation and want to explore the field from the molecular side and experimental models to brain imaging. Join us in Obergurgl and meet young and senior PIs

A great Winter School for those interested in neurodegenerative disorders

Cette nuit, près de Dunkerque, un policier a ouvert notre véhicule de maraude, bloqué la tête d’une bénévole contre le volant et tiré à blanc à trois reprises. Notre équipe a cru mourir. Une plainte va être déposée ⬇️

FREE AFGHAN WOMEN ! Cette photo aux #JOParis2024 rendons la virale ! #FreeAfghanWomen

Incredible work. F8-2 VHH, Hybrigenics Services selected with Isabelle, Clement & Elian against TAU, was switched by @w_mcewan to a subtitle degradon! Power of intabodies.

Protein-protein interaction for subtil interaction in symbiosis. Hybrigenics Services is proud to have contributed. Our customers are fantastic.

📢 [ SAVE THE DATE ] #NLSDays 2024! Join our colleague in Malmö, Sweden, on Sept 18-19 at the Choose France Pavilion, stand C05! Discover Hybrigenics Services platforms for #ProteinInteractions, #DrugDiscovery, #TargetDeconvolution, and #TargetedProteinDegradation. 🔗

🚨 Job alert 🚨 2 years fully funded post-doc position to work on #HIV #latency in the lab of Stéphane Emiliani Institut Cochin, Paris If you are a #transcription and molecular #virology lover, don’t hesitate to apply to meet a fantastic team and do great science ! 🤩

Co-opting templated aggregation to degrade pathogenic tau assemblies and improve motor function Cell So glad to see this paper out. Huge congrats to Guido Papa, Lauren Miller, Leo James' Lab & @w_mcewan (all the teams) for this tour the force! Awesome! cell.com/cell/fulltext/…

The UK DRI's @w_mcewan & Leo James' Lab (@MRC_LMB) have developed new therapies that selectively remove aggregated tau proteins - harnessing the unique capabilities of a protein called TRIM21. The treatment improved symptoms of neurodegeneration in mice👉buff.ly/47ogpFG

Very happy to share our paper describing the selective degradation of aggregated tau protein via clustering activated RING-Nanobody (R-Nb) constructs. Intracellular R-Nb expression prevented tau aggregation and rapidly removed preformed aggregates. science.org/doi/10.1126/sc…

🚀 [ ️THE VHH TOOLBOX ] Revolutionizing Tau research with our Nanobodies® expertise ! Our VHH toolbox offers a cutting-edge selection of #nanobodies to target Tau & other proteins. Starting with an NMR-based 2N4R Tau model, we’ve developed nanobodies like F8-2—a breakthrough in

Raphaël et son équipe développe des stratégies dépassant certaines limites d'AlphaFold lorsqu'il s'agit de déterminer la structure d'assemblages de protéines impliquant des régions intrinsèquement désordonnées. Jessica Andreani Diego Javier Zea joliot.cea.fr/drf/joliot/Pag…

I’d never imagine seeing a pipette in a museum but I’m glad it’s the one that saved the world

🌱 [ The power of plants in research ] Arabidopsis thaliana sheds light on stomatal immunity Researchers from The Sainsbury Laboratory, Durham University , and Universität München have identified the role of NET4A & NET4B proteins in stomatal closure, key for plant defense against drought &

Remembering the first woman to be awarded a Nobel Prize, the first individual to be awarded two Nobel Prizes and still today the only individual with two Nobel Prizes in two different scientific categories: Marie Skłodowska Curie. Curie was born #OnThisDay in 1867.

🔬 [The Power of Plants in Research] Key Discovery in Plant Immunity with our MBmate solution ! Researchers at John Innes Centre identified the PDLP–NHL3 complex as a crucial hub for closing plasmodesmata, blocking pathogen spread. With our MBmate screen, they pinpointed NHL3 as a

🌱 [The power of plant in Research] Triticum aestivum reveals its molecular secrets of immune recognition. Using our ULTImate Y2H screen, researchers explored how the wheat immune receptor Pm2a recognizes the fungal effector AvrPm2. They discovered that TaZF, a zinc finger