Excited to share my first poster as a PhD student with Charleston Chiang & Nicholas Mancuso at #BOG21. Please join me at #103 to chat about our study using summary statistics to estimate heritability explained by local ancestry and stratification bias in admixture mapping studies.

Excited to share this work where we performed multi-ethnic GWAS of acute lymphoblastic leukemia and identified three novel risk loci! medrxiv.org/content/10.110…

Another GWAS demonstrating that you can get novel results from small N if the subjects are from an understudied population 2 new metabolite genes, GLPTD2 and CERS5, from only 650 subjects biorxiv.org/content/10.110… May Montasser Minoo Bagheri

Analyses in this study led by a fantastic collaborator @Linda_Kachuri, along with help from Soyoung Elizabeth Jeon, Charleston Chiang, and others Population and Public Health Sciences at USC USC Norris Comprehensive Cancer Center #childhoodleukemia #ChildhoodCancerAwarenessMonth

Excited to see my first paper out! nature.com/articles/s4137… Big big big thanks to Charleston Chiang Adam de Smith for all the help along the way!

Happy to present our matters arising Nature Genetics re Tractor (Atkinson et al NG 2021). We argue that Tractor reduces GWAS power in admixed pops in realistic settings and we recommend caution when using it for GWAS in admixed pops. rdcu.be/cB2U7 🧵 1/

In a prospective study, a smartwatch-based alerting system was able to detect pre-symptomatic and asymptomatic #SARS-CoV-2 infection in a high percentage of cases. @Spakho Michael Snyder, PhD Stanford University Stanford Medicine #COVID19 nature.com/articles/s4159…

Thrilled to share my first paper from my PhD, advised by Jonathan Pritchard and in close collaboration with my co-first author Shaila Musharoff, on testing for differences in causal variant effect sizes across populations. biorxiv.org/content/10.110… (1/9)

"Portability of 245 polygenic scores when derived from the UK Biobank and applied to 9 ancestry groups from the same cohort" is now published in AJHG 🎉 authors.elsevier.com/a/1eNDcgeW%7Ej… 🙏co-authors H. Aschard, Shai Carmi, lassefolkersen, C. Hoggart, Paul O'Reilly, and Bjarni Vilhjalmsson 1/6

multi-ancestry TWAS improves power for causal gene identification - software (github.com/mancusolab/foc…) outputs causal genes using eQTL weighted GWAS sum stats. Good news - causal genes are more likely to be shared across ancestries(in blood traits). biorxiv.org/content/10.110…

This week in Nature: Human pangenome – data from 47 individuals combine to create reference resource that reflects human diversity. Browse the full issue: nature.com/nature/volumes…

Why do Latino children have the highest risk for childhood leukemia in the US? We identify one cause for this in a paper out in Cell Genomics today, led by Adam de Smith, Lara Wahlster, Soyoung Elizabeth Jeon, Fulong Yu, Charleston Chiang, & colleagues: cell.com/cell-genomics/…

Excited this work is finally out, where we dug deep into a single locus that partly explains elevated risk of childhood leukemia for Latinos. My lab focused on the epi- and evolutionary analysis, primarily driven by Soyoung Elizabeth Jeon, with help from Tsz Fung Chan and @j__langie.

A cell type-aware framework for nominating non-coding variants in Mendelian regulatory disorders nature.com/articles/s4146… #journals #feedly