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NEW OPEN ACCESS: Concentration–effect relationship for tranexamic acid inhibition of tissue plasminogen activator-induced fibrinolysis in vitro using the viscoelastic ClotPro® TPA-test. New study by Dibiasi et al #coagulation #TXA #Clot-pro bjanaesthesia.org/article/S0007-…

Check out this insightful editorial by Kenichi Tanaka et al on the value of #Clotpro and its unique #TPA-test. This test helps in dose-response assessment to TXA. The findings are a testament its clinical utility. Read more: lnkd.in/gjRbyxey.

From myself & and the team at Haemoview, we wish everyone a safe, joyful, and fun-filled Christmas.

Sydney ! 🇦🇺 2 . 0 . 2 . 4 🥂🎇

Looking forward to a bright 2024

Fibrinolytic shutdown (versus hypofibrinolysis) = plasmin burst followed by diminished fibrinolysis. After thrombin and plasmin burst, fibrinolysis is inhibited, mediated by increased TAFI Julia R Coleman, MD MPH Ohio State Wexner Medical Center Surgery Dept. CU Department of Surgery Mitchell Jay Cohen #TAFI journals.lww.com/jtrauma/citati…

Good to see #clotpro becoming integrated into widespread use . Being able to incorporate the device specific tests makes it top of its class link.springer.com/article/10.100…

📷 Using #ClotPro #TPAtest, patients undergoing cardiac surgery who demonstrated an association between the severity of fibrinolysis resistance on the first post-operative day, required extended postoperative ICU level support. Check out the study:onlinelibrary.wiley.com/doi/10.1111/aa…

Venous thromboembolism (VTE) is a major problem in trauma patients and earlier prophylaxis is thought to be better. But how much better is it? Should 'door-to-prophylaxis' time be a quality metric for trauma centers? Van Gent et al explore this: ➡️tsaco.bmj.com/content/9/1/e0…

AAST 2023 Podium. Out today in Troy Staples. Incredible work by Mike Van Gent showing every 1-hr delay in initiation of chemoprophylaxis was associated 1.5% increase in VTE

From the same peeps that told u NOACs were better, didn’t need antidotes, didn’t need labs. ⬆️ clot events, ⬆️ ischemic stroke, no diff in modified Rankin or 💀 in 30d Andexanet for Factor Xa Inhibitor–Associated Acute Intracerebral Hemorrhage | NEJM nejm.org/doi/full/10.10…

Elucidating the molecular mechanisms of fibrinolytic shutdown after severe injury: The role of thrombin-activatable fibrinolysis inhibitor dlvr.it/T7GwCv

A privilege to be given the opportunity to talk at ISTH #ISTH2024 Especially in the same session as the Excellent Prof’s Brohi Karim Brohi and Curry Nikki Curry Thank you 🙏🏼 ISTH