Crystal structure of a murine antibody complexed to cocaine (PDB code: 1Q72) #molecularart #scivis #sciart 3D Protein Imaging Stylar
behance.net/gallery/198901…

cryoEM structure of the rat SUR1/Kir6.2-Q52R ATP-sensitive potassium channel in an open conformation (PDB code: 8TI1) #scivis #sciart #molecularart 3D Protein Imaging Stylar
behance.net/gallery/198835…

Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface. Nature Communications 15, 2502. Check the #cryoEM #structure of this #ABC #transporter in the UniTmp database: pdbtm.unitmp.org/entry/8ti1

An example of a parallel beta-sheet structure, exemplified by the crystal structure of a bacterial alginate epimerase/lyase (PDB code: 8XFR) #scivis #molecularart #sciart 3D Protein Imaging Stylar
behance.net/gallery/198728…

CryoEM model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening state, as part of a complete study published in PNAS by He and coworkers (PDB code: 8UMV) #scivis #sciart #molecularart 3D Protein Imaging Stylar
behance.net/gallery/198570…

Crystal structure of an RNA hexamer UUCGCG exhibiting a non-canonical Hoogsteen base pair connection (PDB code: 1OSU) #scivis #molecularart #sciart 3D Protein Imaging Stylar
behance.net/gallery/198534…

“Illuminating ‘the ugly side of science’: fresh incentives for reporting negative results.”
nature.com/articles/d4158…

Great model building by #alphafold3 showing the chaperone-usher system involved in pili biogenesis from Klebsiella pneumoniae, compared with the experimentally available data from E.coli (PDB code: 4J3O) #scivis #building #pili #chaperone #usher

CryoEM structure of the FimD usher from Escherichia coli involved in pili biogenesis (PDB code: 6E14) #scivis #molecularart #sciart 3D Protein Imaging Stylar
behance.net/gallery/198433…

Example showing how a Tryptophan residue is use to stabilize a protein-protein interaction, exemplified by the crystal structure of NS2B-NS3 protease from Zika Virus (PDB code: 7H25) #scivis #moleculart 3D Protein Imaging Stylar
behance.net/gallery/198392…

Using 250 lipids as input, @alphafold3 produces very interesting output, including a micelle, with quite rigid conformations of lipids. #scivis #lipids #micelle 3D Protein Imaging

Crystal structure of the Campylobacter jejuni multidrug efflux pump CmeB (PDB code: 5LQ3) #scivis #molecularart #sciart 3D Protein Imaging Stylar
behance.net/gallery/198330…

Curious effect in alphafold predictions of membrane systems. The increase of the number of lipidic elements favours the formation of micelle-like structures and forgets the protein-lipid interaction. #membrane #prediction #lipids

Crystal structure of the monoheme cytochrome from Rhodotermus marinus (PDB code: 3CP5) #scivis #molecularart #sciart 3D Protein Imaging Stylar
behance.net/gallery/198289…

Prediction of the structure of the human microprocessor for miRNA biogenesis using alphafold. Useful insights about the putative interaction interface between Drosha and DGCR8 proteins. #prediction #model #miRNA #drosha #dgcr8

AlphaFold3 is out with improvements on structural models that include DNA/RNA and small molecules. Unfortunately, there is no code, no binary to run at scale and only a limited webserver. Why even publish? nature.com/articles/s4158…

We're excited to announce #AlphaFold 3 with Google DeepMind in nature: our new AI model for predicting biomolecule structures with unprecedented breadth and accuracy.

Expanding beyond proteins to tackle DNA, RNA, small molecules to fuel advances in biology & drug design 🧵

Crystal structure of an antigenic outer membrane protein ST50 from Salmonella Typhi (PDB code: 5BUN) #scivis #sciart #molecularart 3D Protein Imaging Stylar
behance.net/gallery/198095…

Sr. Díaz Villanueva.. Para cuando una contrahistoria del 25 de Abril?... Aproveche que hace 50 años... Le escucho, como exiliado en Lisboa y seguidor fiel.

Happy to share SHAPEwarp-web, a webserver for SHAPE-guided #RNA structure homology search, featuring a fully-rewritten SHAPEwarp core (2 orders of magnitude faster)! We hope this will be a first step towards a 'BLAST for RNA structure'. Check it out: doi.org/10.1093/nar/gk… (1/n)