New paper 'Alcohol consumption and the risk of all-cause and cause-specific mortality—a linear and nonlinear Mendelian randomization study' at IJE: academic.oup.com/ije/article/53… led by Nigussie Kassaw and Elina Hyppönen. Brief thread:

4 years ago, we ran 16,554 GWASes for 7,271 traits across 6 ancestry groups and released the data to the public along with meta-analysis. After many careful dives through the results, we are happy to present these analyses on behalf of the Pan-UKB Project: medrxiv.org/content/10.110…

The genetic ancestry labels that the NIH “All of Us” biobank genetic data returns seem likely to add to general confusion about genetics and race/ethnicity [see appendix A here: researchallofus.org/wp-content/the…] 1/n

Presenting µBrain: a 3D atlas of Allen Institute histological slices of the developing brain, and tools for aligning gene expression/brain imaging! A beautiful labor of love led by Gareth Ball

DevelopingConnectome Stuart Oldham Aaron Alexander-Bloch Emma R - @metricsemma.bsky.social & others!

biorxiv.org/content/10.110…

(1/7) We have developed a new method, DDx-PRS, to distinguishing different clinically related disorders based on polygenic prediction medrxiv.org/content/10.110…

Distinguishing different psychiatric disorders using DDx-PRS medrxiv.org/content/10.110…

There is an opening for a postdoc in my lab at UT Austin to work in the areas of statistical genetics and mental health and/or cognitive aging. Funding is in place. Our recent work can be found at lifespanlab.com. Please feel to email me directly. [email protected]

Yale University researchers are inviting volunteers to participate in a paid brain imaging study on decision-making and eating behavior. Please email [email protected] or visit our website for more information! medicine.yale.edu/ycci/trial/gut… Yale School of Medicine #eatingdisorders

🚨 New paper!
In this review, we explore factor indeterminacy and outline how we can use genetic data to test the validity of latent factors.

nature.com/articles/s4156…

With Ted Schwaba, Elliot Tucker-Drob, Kathryn Paige Harden, Andrew Grotzinger, and @michelnivard

New paper by Andy Dahl and I on phenotype integration improving GWAS power while preserving specificity is now out in Nature Genetics 🎉 thank you all collaborators and reviewers! nature.com/articles/s4158…

Our new study of cannabis use disorder (N>1,000,000) led by Dan Levey is now online at Nature Genetics.

Article here:
go.nature.com/49Nj1Ou

Sumstats will be made available here:
- dbGAP (bit.ly/47kgf1u)
- Gelernter Lab Webpage (bit.ly/3ETJWJU)