AD was not even considered a disease by the majority of clinicians & scientists.

Even after recognized as a disease, genetics was not considered a factor affecting the onset or progression of Alzheimer’s disease.

Huge progress, thanks to pioneers against the dogma🙌🍾

'Assuming a mouse weighs 20 g, the dose per mouse is 0.002 mL, and a dose so small is nearly impossible to measure and inject with confidence into the peritoneal space.'
journals.lww.com/clinorthop/ful…
I agree😏 How can you accurately inject ***2 uL*** intraperitoneally?🤯

'Arrays reveal long noncoding RNAs (lncRNA) are neither sparsely nor lower expressed than protein coding genes.' 🙄

Critical point to keep in mind.
The timing of sample collection matters! Kinetics of mRNAs & Proteins is different.
Having said that, we had a few projects in which a list of differentially abundant proteins was almost identical to a list of differentially expressed mRNAs!

'Journals should require pre-registration — a time-stamped research plan, submitted before analyzing the data — which should discourage fiddling with figures to suit preferred outcomes.'
Funding agencies should require pre-registration of animal studies too! NIH

A list of conditions that cause childhood dementia
Let's do something for these kids!
childhooddementia.org/childhood-deme…

A staggering 44.8% of Fortune 500 companies, equating to 224 companies, have been founded by immigrants or their children.

Source: americanimmigrationcouncil.org/research/new-a…

Please join us!
Welcome to Korea 🇰🇷

Almost accepted a Director and a Senior Director position from big biotech companies a few times but ended up declining offers.
At least for now, more to lose by jumping into the other side.

Exactly 💯 💯 💯

Glad to see one more person agrees with me!!!
NIH should push out this policy!!!
'Questionable Research Practices, Low Statistical Power, and Other Obstacles to Replicability: Why Preclinical Neuroscience Research Would Benefit from Registered Reports'
eneuro.org/content/9/4/EN…

[NIH/NINDS] Novel Approaches to Preventing Publication Bias Workshop
ninds.nih.gov/news-events/ev…

Hirano bodies are intracellular aggregates of actin & actin-associated proteins. I heard about this term for the first time while collaborating with an outstanding EM expert, Dr. Krikor Dikranian. Learned a lot from him!
ncbi.nlm.nih.gov/pmc/articles/P…

Not sure it is the 'BEST' kind of science😅 but we certainly embraced the uncertainty🧐
This project wouldn't have been possible without his resilience and the tremendous help & guidance by Hande Karahan & the thesis committee members who brought valuable expertise in obesity &

Against graduate students on strike, asking for livable pay🤯
[***Not*** IU Medical school]

“Participation in a work stoppage,” Shrivastav wrote, “will result in non-reappointment to future Student Academic Appointments.”
idsnews.com/article/2024/0…

Lifelong absence of microglia alters hippocampal glutamatergic networks but not synapse and spine density | EMBO reports embopress.org/doi/full/10.10…