How a neutral trial is covered in the medical press: medpagetoday.com/hematologyonco… #MePFAC Ollie Minton

Methylphenidate Versus Placebo for Treating Fatigue in Patients With Advanced Cancer: Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial last week we were still sitting on this ⁦Tim Williams⁩ ⁦My Clinical Outcomes⁩ 😎🍾 #fridayfeeling ascopubs.org/doi/10.1200/JC…

Methylphenidate Versus Placebo for Treating Fatigue in Patients With Advanced Cancer: Randomized, Double-Blind, Multicenter, Placebo-Controlled Trial | Journal of Clinical Oncology cheers 🍻 Matthew Katz, MD 🟦 enjoy #ASCO2024 ascopubs.org/doi/10.1200/JC…

Open Access UCL Research: Specialist physiotherapy for functional motor disorder in England and Scotland (Physio4FMD): a pragmatic, multicentre, phase 3 randomised controlled trial discovery.ucl.ac.uk/id/eprint/1019…

UCL Marie Curie NIHR Research EAPC VZW Journal of Clinical Oncology Amazing stuff regardless we did what we set out to do Louise Marston UCL Psychiatry UCL Primary Care & Population Health Priment Clinical Trials Unit and a multi centre RCT in #PalliativeCare time 🕰️ to do more done is the engine of always I’d even be CI if it helps

Listen to Prof Stone (CI of the trial) discuss the #mepfac results.

Full results: ascopubs.org/doi/full/10.12…

Editorial: ascopubs.org/doi/10.1200/JC…

Podcast: jcopodcast.libsyn.com/methylphenidat…

NIHR Research EAPC VZW Journal of Clinical Oncology #pallonc

ascopubs.org/doi/10.1200/JC… associated editorial Journal of Clinical Oncology NIHR Research Macmillan Cancer Support EAPC VZW UCL Marie Curie #fatigue #pallonc so that’s podcast paper 📝 oral presentation and everything we win 🏆 We are NIHR Dr Nicola White Prof. Mark Taubert UHSussexResearch mines now a chair 🪑

Phase III trial methylphenidate versus placebo for cancer fatigue in advanced solid tumors - Jarushka Naidoo
Journal of Clinical Oncology
oncodaily.com/68764.html

#Cancer #Oncology #NSCLC #OncoDaily #Cancer Research

Read our NIHR Research funded RCT on the effectiveness of methylphenidate versus placebo for cancer fatigue. Over 10 years of work.

Published in Journal of Clinical Oncology

doi.org/10.1200/jco.23…

Marie Curie EOLC UCL Psychiatry

Thanks for your insight on our Data Monitoring Committee #MepFAC UCL Marie Curie Ollie Minton

Methylphenidate for Fatigue in Advanced Cancer | ASCO Publications ascopubs.org/do/methylpheni…

Did Kingston Bear Trail yesterday. Kingston upon Thames Wild in Art Pity Clarence was so badly damaged. flic.kr/s/aHBqjBqYEA

Excellent trial and results honestly reported by my colleagues at UCL Marie Curie.

I’m in awe of the way that Glenn Nielsen developed FND focused physio treatment from first principles, led consensus recommendations, did a pilot trial and has now led this huge trial across the Uk 👏👏👏👏👏👏

Specialist physiotherapy was found to be no better than community physiotherapy at improving physical function. Participants in both groups improved and both treatments were highly valued. The secondary outcomes show some additional value from the specialist treatment.

We also found promising outcomes in a health economic analysis, which we will publish shortly… So what does this all mean for people with FMD and physiotherapists providing treatment for people with FND?

Other trial outcomes at 6- and 12-months can be seen in this figure. Outcomes to the right of the 0 line favour specialist physiotherapy. Confidence intervals clear of the line are statistically significant.

Some of the secondary outcomes favoured specialist physiotherapy over treatment as usual physiotherapy, including a participant rated impression of improvement where 59% of specialist physiotherapy participants rated their symptoms as improved vs 38% of treatment as usual.