Do we really need cyclophosphamide for #lupus_nephritis ?

⁦Pediatric Nephrology⁩ ⁦Scott Wenderfer⁩ link.springer.com/article/10.100…

IgA nephropathy is a genetically complex multifactorial trait. Over the past decade, population-based genome-wide association studies have identified >30 IgAN risk loci. Read this Review of the state of genetic research in IgAN.
link.springer.com/article/10.100…

Important paper about improving adherence to antihypertensive medications! International Pediatric Hypertension Association International Society of Hypertension American Society of Pediatric Nephrology Tammy Brady Swapnil Hiremath @[email protected] European Society of Hypertension Dr Anastasia Mihailidou FAHA FCSANZ FESC BAPN ESPN

HUS may cause AKI in children. Patients may present w/kidney abnormalities years after HUS recovery. Read this Original Article on the long-term outcome of Shiga toxin-producing Escherichia coli-associated HUS in pediatric patients. #OpenAccess
link.springer.com/article/10.100…

Nuclear factor kappa B family plays a central role in the human immune system. Heterozygous variants in NFKB2 typically cause immunodeficiency. Read these Clinical Insights on a novel NFKB2 variant w/hypertension & nephrotic syndrome leading to CKD 5D.
link.springer.com/article/10.100…

Don't miss it!

Medication fill duration in pediatric #hypertension : adherence, blood pressure control, and disparities

⁦Pediatric Nephrology⁩ #BP link.springer.com/article/10.100…

A special CKiD Study paper that I'm so pleased is supported by NIDDK, @kidney_int, Ryan Town 🤏🏽🫘.

This tool helps predict pediatric CKD progression to KRT (online at kidney.wiki). We did our best and our hope is that it is useful for clinicians treating ped CKD.

Levamisole is a common steroid-sparing agent (SSA) but the incidence of antineutrophil cytoplasmic antibody (ANCA) positivity is concerning. Read this Original Article on children 2-18 y.o. w/FRNS/SDNS on levamisole for ≥1 year who were tested for ANCA.
link.springer.com/article/10.100…

1/12 - Mystery #1

You are seeing a patient recently diagnosed with heart failure and started on GDMT. You notice that their hemoglobin (HGB) has increased (12 → 13 g/dL) in the intervening weeks.

🤔Which medication is the likely cause of this increase in HGB?

Lowe syndrome is characterized by congenital cataracts, psychomotor retardation & dysfunctional proximal renal tubules. Read this Original Article on atypical phenotypes & genetic characteristics of 8 children w/Lowe syndrome in southern China.
link.springer.com/article/10.100…

Are you a practice administrator/practice manager? If so, please make sure you register for RPA's 2024 Annual Meeting which features a business management track for practice administrators and practice managers.

ICYMI, NIDDK-supported CKiD Study built a prediction tool to accurately estimate when children with #ChronicKidneyDisease need kidney replacement therapy (KRT), which will guide clinical planning & treatment. Led by Derek K Ng Johns Hopkins Bloomberg School of Public Health Kidney International pubmed.ncbi.nlm.nih.gov/37391041/

An awesome sight for sure! #TotalSolarEclipse2024

Idiopathic nephrotic syndrome (INS) is the most common glomerular disease in children. Read this Original Article on histopathological findings, response to steroids & other immunosuppressive drugs, & outcomes in Syrian children w/INS.
link.springer.com/article/10.100…

Metabolic acidosis is associated with an accelerated decline of allograft function in #pediatric #kidney #transplantation
kireports.org/article/S2468-…

I cannot describe how happy it makes me. Beyond the 👑, smart, rich discussion with brave nephrologists, I hope this will pave to way for accelerated approval by authorities in all parts of the🌐

Should we make it official#️⃣? #glipinate #NephMadness 🦎

Not too shabby - thanks to Gila The NephMadness Monster! #NephMadness

Animal house finally did it!! You go Gila

The blue ribbon panel redeemed itself #NephMadness