Exciting replication indeed! The same genetic locus affects voice pitch in tonal (mandarin) and non-tonal languages (Icelandic). Sidenote: variants at this locus differ substantially in frequency across populations...less frequent in pop. with tonal languages (AFR, EAS)

Really interesting conversation by Michel and Eiko (Eiko Fried) on our latest GWAS of depression. Fantastic primer on why GWAS matters and what it's trying to do, followed by some insightful criticism that we can definitely learn from
youtu.be/vHvBzFQWqRg?fe…

Thanks Holden for being a role model for autistic people worldwide. Your willingness to share that you are autistic and Editor in Chief of Science, one of the premiere journals in our field, will inspire and empower many people & celebrates neurodiversity science.org/doi/10.1126/sc…

I’m thrilled to share the new preprint I’ve written with Christian D. Huber and Matthew Williams about the human transition from foraging to agriculture! biorxiv.org/content/10.110… Please see the following thread about the work below! 🧵

Happy to share that our most recent work on North African Imazighen is out now on Scientific Reports!! 🥳🥳🥳 I'm very grateful to all the collaborators involved in the project!

nature.com/articles/s4159…

Institute of Evolutionary Biology (IBE) UPF Medicine and Life Sciences UPF Barcelona

Now published in Nature Mental Health!
nature.com/articles/s4422…

Main difference since the first preprint was posted: we now have results for #autism as well! Results are similar to Bipolar and OCD 🧵👇

I am very proud and happy to say that I successfully held my trial lecture and defended my PhD thesis on Tuesday 🥳👨‍🎓. The day was made extra special by the presence of many friends, family members, and colleagues who showed their support.

New pre-print from the PGC Consortium #Depression Group: Multi-ancestry GWAS of depression with 685,000 cases identifies 697 independent associations, implicating known & novel drug targets.

🔗 medrxiv.org/content/10.110…

1/n

Our SBayesRC method is now published in Nature Genetics! SBayesRC is a full Bayesian method for polygenic score prediction that can analyse all common variants jointly with functional annotations in a single step. Zhili Zheng Institute for Molecular Bioscience nature.com/articles/s4158…

New paper out in Frontiers on Gene x Environment interaction in self-control in adults! Collab between #MPRGBiosocial and Netherlands Twin Register, with the amazing Laurel Raffington, PhD,Meike Bartels & co. Based on the last chapter of my dissertation🎓Check it out here 👉doi.org/10.3389/fpsyt.…

👀 sv.uio.no/psi/forskning/…

Additive effect of carrying multiple rare variants in monogenic DDG2P genes and common variant polygenic score for educational attainment in UK Biobank. Lovely work from former PhD student Becca Kingdom with Mike Weedon Exeter Med School Nature Genetics
doi.org/10.1038/s41588…

Two new chapters from my open-access textbook in human population genetics are now online:
- Population structure: I. Ancestry estimation
- Population structure: II. More about admixture
web.stanford.edu/group/pritchar…

Our paper “Investigating the role of cis-eQTLs in modifying the penetrance of putatively damaging, inherited variants in severe neurodevelopmental disorders” (NDDs) is out in Scientific Reports! Three interesting findings led to this study: nature.com/articles/s4159…

We wrote a brief commentary on Carrasquilla et al.'s recent MR paper where they find that smoking initiation and lifetime smoking may causally increase abdominal adiposity (in contrast to prior findings): doi.org/10.1111/add.16…

🧬🧬Distinct genetic pathways to music enjoyment 🎶🎶

🙋‍♂️Laura Wesseldijk Ernest Mas Herrero Zatorre Ullèn Simon Fisher & Mosing

biorxiv.org/content/10.110…

Postdoc position to join my new group Oxford Psychiatry and Big Data Institute. UKRI funded 'CHECKPOINT: Finding immune & metabolic pathways to SMI' led by Ed Bullmore, direct supervision from Mary-Ellen Lynall collaborating with Andrew McIntosh . my.corehr.com/pls/uoxrecruit…

When we think of recessive conditions, rare monogenic disorders come to mind. Yet variants have recessive effects on common diseases too! We profiled the single-variant recessive landscape of a cohort of 44k British South Asians, now live on medRxiv:
(1/11)

Congratulations to my student Teng Hiang on her first PhD preprint! It's about recessive associations in Genes & Health , a cohort of >40k British South Asians. See her thread for an account and the paper here medrxiv.org/content/10.110….

Scientists sequenced Beethoven's genome from a strand of hair and found a funny result.

Applying the gene-wide associations studies to musicality (that we know, there are methodological limits), Beethoven's genetic propensity to musicality was... low?