Super excited to announce that Mike Mitchell MD PhD student Rohan Palanki roro 's thesis defense titled 'Ionizable lipid nanoparticles for in utero gene editing of congenital disease' is this Wednesday at 1PM!

Link to location and Zoom: bit.ly/49jPUS5

Check out our latest in Advanced Materials Advanced Sci News led by Mike Mitchell PhD student Ann Metzloff on antigen presenting cell-mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy!

Free access: onlinelibrary.wiley.com/doi/10.1002/ad…
Penn story: blog.seas.upenn.edu/accelerating-c…

Check out our latest in Advanced Functional Materials Advanced Sci News led by Mike Mitchell PhD student Alvin Mukalel Alvin Mukalel on new oxidized mRNA lipid nanoparticle tech for making CAR monocytes in the body for cancer immunotherapy!

Free access: onlinelibrary.wiley.com/doi/10.1002/ad…

Excited to share my review article on nanomedicine in autoimmunity, now out in ADDR! Thank you to Maggie Billingsley, PhD Jilian Melamed The Drew Weissman Lab and Mike Mitchell for being the best support system! Looking forward to exploring this area further 🔬

Congratulations to Sonja Schrepfer and the team at Sana for curing a nonhuman primate with allogeneic islets without requiring immunosuppression! cell.com/cell-stem-cell…

Wonderful review by Mike Mitchell Carl June, Karin Wang and associates on 'Responsive Biomaterials: Optimizing Control of Cancer Immunotherapy' in Nature Reviews Materials scholar.google.com/scholar_url?ur…

Thrilled to announce that my first review on responsive biomaterials for cancer immunotherapy is now out in NatRevMaterials! Special shoutout to my partner-in-crime Lulu Xue, Ph.D for being the best co-author and to the entire Mike Mitchell team for their support!

So excited to have my final first author paper from my PhD in Mike Mitchell at Penn Bioengineering come out this weekend in Small!

Using antibody functionalized lipid nanoparticles, we demonstrate in vivo T cell transfection for CAR T cell engineering 🧫 🧬

onlinelibrary.wiley.com/doi/10.1002/sm…

Huge congrats to Mike Mitchell PhD student Ajay Thatte Ajay Thatte for being featured on the cover of Nano Letters for his new mRNA lipid nanoparticle tech to engineer T cells to treat autoimmune diseases!
Issue link: pubs.acs.org/toc/nalefd/23/…
Article link: pubs.acs.org/doi/10.1021/ac…

Check out our latest in Theranostics Theranostics led by former Mike Mitchell undergrad Savan Patel Savan Patel on a new bile acid lipid nanoparticle platform to enhance mRNA delivery beyond the liver!

Free access: thno.org/v14p0001.htm

Link to Nano Letters article: pubs.acs.org/doi/10.1021/ac…

So excited to share my first research article on mRNA LNPs for engineering immunosuppressive T cells for applications in autoimmunity! A big thanks to the entire Mike Mitchell team that made this possible!

Thrilled to share our latest in PNAS PNASNews led by Sarah 'Scaleup' Shepherd (co-advised with david issadore) on SCALAR: a new microfluidic platform for throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines!

Free access link: pnas.org/doi/10.1073/pn…

Check out our latest paper published in Small Advanced Sci News led by Mike Mitchell PhD student Hannah 'Coach' Safford Hannah Safford on orthogonal design of experiments LNP optimization for in vivo mRNA delivery to the placenta during pregnancy!

Link: onlinelibrary.wiley.com/doi/10.1002/sm…

Check out our latest ACS Nano with William Peranteau's lab led by our MD PhD student roro on new mRNA LNPs for in utero and postnatal base editing in the brain to treat congenital disorders! Rohan is presenting his work at GRC Biomaterials this week!
pubs.acs.org/doi/10.1021/ac…

So thrilled to share my first review article written with the amazing Hannah Safford — we are excited to shed light on nanomedicine strategies for pregnancy complications in the current post-Roe era

Super excited to share my first review on nanomedicine strategies to treat and diagnose placental disorders! Had an amazing time writing this with my fabulous co-author Hannah Geisler

Check out our latest publication in Small Advanced Sci News co-led by Mike Mitchell PhD students Hannah Geisler Hannah Geisler + Hannah Safford Hannah Safford on rational design of nanomedicine for women's reproductive health applications!

Link to article: onlinelibrary.wiley.com/doi/10.1002/sm…

Avengers assemble from Mike Mitchell Wang Lab and Omid Veiseh labs to cap off #SFB2023 ! Huge thanks to Elizabeth Cosgriff-Hernandez Christman Lab for putting together an amazing SFBiomaterials meeting!

Along with 7 posters on Thursday and Friday at #SFB2023 on mRNA LNPs for liver fibrosis, autoimmunity therapies, CAR T cell, and CAR monocyte engineering (2/3)