Luke O'Connor
@Luke0connor
Statistical genetics - Genetic architecture and disease biology - Assistant Professor @HarvardDBMI - he/him
ID:719341751593512962
http://oconnor-lab.org 11-04-2016 01:50:13
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Long non-coding RNAs comprise a large part of the genome, yet loss of one copy (haploinsufficiency) of a lncRNA is not known to cause a human disease. Read our preprint to learn how deletions of the lncRNA CHASERR cause a severe neurodevelopmental disorder.medrxiv.org/content/10.110…
How stable are bacterial genomes as they adapt to an environment? My collaboration with Anurag Limdi, Alex Couce, Richard Lenski, and Olivier Tenaillon exploring this over 50,000 generations of evolution is out today!
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science.org/doi/10.1126/sc…
Yet again--to nobody's surprise--Jay Shendure & co blow several fields'-worth of minds in a single paper 🤯🤯
Remarkable combination of cool tech + important but understudied problem
Tech like this will transform our understanding of how SVs impact cellular phenotypes & fitness!
Our germline mutation rate model have been published in Nature Genetics. Together with methods to estimate mutation rate, we designed novel validation metrics and characterized hypermutability associated with Pol III transcription.
'Nothing has prepared me for the antisemitism I see on college campuses now,' new from UC Berkeley Law Dean Erwin Chemerinsky. latimes.com/opinion/story/…
Behind a paywall, but here's the beginning.
For the same reasons, I too will resign as reviewing editor at eLife - the journal.
Like Michael Eisen, I am crushed by what happened in Israel and also deeply concerned about what is unfolding in Gaza.
🧬Join us in Boston Oct 17-18, 2023 for the
HarvardPQG Conference on Diversity in Genetics & Genomics. We have an amazing lineup of speakers: hsph.harvard.edu/pqg-conference…
📢Abstracts due September 25, 2023