Founded by world-leading immunologists Miriam Merad, MD, PhD, Sacha Gnjatic, Seunghee Kim-Schulze, & Erik Wambre, OCCAM Immune offers biobanking and cutting-edge tools tailored for discovering immune biomarkers for patient stratification and the etiology of immune-mediated diseases.

Study in Nature Communications by HabermanLab on the Urban-Rural diet-omic roots of IBD in China/Israel (our SOURCE Helmsley Charitable Trust consortium). Shows a gradient of IBD-like microbiome change correlating with time in city spent by villagers.
doi.org/10.1038/s41467…
Sheba Medical Center

PHD STUDENT VISITING NYC 🗽

Linea Bonfils is currently a visiting researcher at Icahn School of Medicine at Mount Sinai. She works with data from the unique MECONIUM cohort.

A big thank you to Manasi Agrawal, MD, MS, Jean-Frederic Colombel, #IngaPeter , and all of Peter lab for welcoming this collaboration.

New paper out in Science showing that the effect of vitamin D on cancer risk goes via the gut microbiome ➡️ jyllands-posten.dk/indland/ECE170…

Tine Jess The Crick Evangelos Giampazolias Caetano Reis e Sousa Danmarks Grundforskningsfond Aalborg Universitet Aalborg Universitetshospital AAU SUND

Colombel: patients who develop #Crohns are serologically different years before diagnosis—PREDICTS study Jean-Frederic Colombel

Thank you for the highlight Science Magazine!

🔦 science.org/doi/10.1126/sc…
📄science.org/doi/10.1126/sc…

REVIEW | Deciphering the different phases of preclinical inflammatory bowel disease

nature.com/articles/s4157…

#IBD #Crohns #colitis

🔬 New #research study from Rachel Levantovsky, PhD 🇺🇦 Ling-shiang (Felix) Chuang, Ph.D. Judy Cho sheds light on #PerianalFistula in #Crohnsdisease patients. Learn about the mechanisms revealed by #SingleCellAnalysis . #MedicalScience sciencedirect.com/science/articl…

Interested in how to predict (and eventually prevent) IBD?

We are not alone!

🧠 Here on Multiple Sclerosis prediction years before diagnosis

👇🏻👇🏻👇🏻

Congratulations to Dr. Arafa Djalal on the completion of her Mount Sinai IBD Center Fellowship! Looking forward to your amazing career that lies ahead!

Ryan Ungaro MD MS Manasi Agrawal, MD, MS Jean-Frederic Colombel Mehandru Lab @MountSinai Alexandra Livanos, MD PhD Jellyana Peraza MD Mount Sinai Division of Gastroenterology

Congratulations to Miriam Merad, MD, PhD, appointed as Dean for Translational Research and Therapeutic Innovation of the Icahn School of Medicine at Mount Sinai.
Miriam Merad, MD, PhD Icahn School of Medicine at Mount Sinai #Immunology #Immunotherapy

🌟Wrapping up day 1 of our 2nd GlycanTrigger General Assembly Meeting in Leiden!💭It is been a productive day with many fruitful discussions🙌WP1, 3, 4 and 6 had the opportunity to report 2023 activities and the action plan for 2024, and discuss their latest research findings🔍

📅 This week, GlycanTrigger team is meeting in Leiden for our 2nd General Assembly Meeting
🔬The project is on a mission to find a way to intercept chronic inflammation by studying how changes in glycans impact the initiation of the inflammatory process
🚀Stay tuned!

When the pouch is sick, who do you call?

Pouchitis-buster Maia Kayal MD takes us on the journey of evidence (& lack thereof) in the realm of IPAAs

Full recordings w/registration #EBMED EBMed.net

Amazing 🗞️ paper abt MoAction one of the most 🔐 precision biologic in #UlcerativeColitis treatment since 2015

🗝️ 🔓 #Vedolizumab

👉 Anti-α4β7 therapy results in a decrease ⬇️ of #naïve B & T cells in🎯 intestinal mucosa of #UC patients

Science Immunology

doi.org/10.1126/sciimm…

Fascinating study on Vedolizumab mechanism of action in Ulcerative colitis in Science Immunology by Mehandru Lab @MountSinai

Saved for reading after the weekend!⛵️

👇🏻👇🏻👇🏻

Unappreciated MOA of vedolizumab with major implications including new perspectives for precision medicine

Gut-associated lymphoid tissue attrition associates with response to anti-α4β7 therapy in ulcerative colitis. pubmed.ncbi.nlm.nih.gov/38640252/

Robert Battat MD Gil Kaplan MD MPH Aline Charabaty, MD, FACG, AGAF Indeed. Our pilot analysis of serum samples from a military cohort also demonstrated a strong association bw PFAS and IBD. Much work to be done in this space. pubmed.ncbi.nlm.nih.gov/38154728/

Presenting at IOIBD annual meeting! What an amazing opportunity!

Combining beauty and great science 👍