Data on outcomes among reproductive-aged women in #ISHLT registry can help guide discussions around pregnancy after HT #CardioObstetrics

@ersied727 @MKittlesonMD Josef Stehlik Heather Ross

🔗: jhltonline.org/article/S1053-…

Metabolomic Profiling During Ex-situ Normothermic Perfusion Prior to Heart Transplantation Defines Patterns of Substrate Utilization & Correlates w Markers of Allograft Injury Lauren K. Truby Adam DeVore, MD, MHS @jacobniall Svati Shah cc @ahajduczok Rachna Kataria, MD

🔗: jhltonline.org/article/S1053-…

The society's flagship journal, The Journal of Heart and Lung Transplantation (JHLT), has named Joseph Rogers, MD, as the new editor-in-chief of the Journal. 📚 Read more about Dr. Roger's appointment at 🔗 bit.ly/3Qsce4K

Congratulations, Joseph Rogers! 🎉

May #JHLTThePodcast is out!
▶️ Racial and gender disparities in #HepatitisC + hearts and lungs with Helen Hannan, a University of Michigan undergraduate
▶️ #Metabolomic profiling during #NRP before #HTX and its ability to predict #allograft injury with Lauren K. Truby
🎧: thejhlt.libsyn.com/episode-42-may…

While statins are used commonly in children after 🫀transplantation, early use was not found to decrease cardiac allograft vasculopathy development or improve graft survival in a propensity matched cohort of children. PHTSociety Madeleine Townsend

🔗: jhltonline.org/article/S1053-…

Acute T cell leukemia in a stable recipient of a heart transplantation. The authors recommend preop survey & regular monitoring of HTLV-1/2 carrier recipients after ❤️tx, given lack of established chemotherapy/antivrial agents for such patients.

🔗 jhltonline.org/article/S1053-…

The new hemodynamic definition of PH markedly reduces the number of patients who may be diagnosed as CTEPD patients without PH; importantly, in such patients pulmonary endarterectomy is clinically futile.

🔗 jhltonline.org/article/S1053-…

Among Expanded Criteria donor hearts, SherpaPak (compared to cold storage) reduced post-tranplant MCS and PGD.

🔗 jhltonline.org/article/S1053-…

BLyS inhibitors were effective in inhibiting B-cell activation/differentiation, reducing antibody production & prolonging allograft survival. BLyS inhibitors could be used for prevention of chronic rejection in practice. cc @ahajduczok Rachna Kataria, MD

🔗 jhltonline.org/article/S1053-…

In this issue, female CTEPH pts. showed worse outcomes after Pulm Endarterectomy. This highlights the need for expanded use of Balloon Pulm Angioplasty, as we have highlighted in previous work. @alexcruzutrilla Hipertensión Pulmonar H12O

🔗 jhltonline.org/article/S1053-…

Changes in RV dimensions are not included in risk predictions post LVAD. A non-adapted RV was associated with alterations TV & RV geometry, leading to worsening TR. This may help identify patients that may be refractory to LVAD therapy. Hideyuki Hayashi
🔗 jhltonline.org/article/S1053-…

We have developed and validated a clinically useful app-based tool for predicting PGD risk for lung transplant recipient Michaela Anderson

🔗 jhltonline.org/article/S1053-…

In a multi-center cohort, the HM3 risk score provided adequate risk discrimination in “trial-like” pts but was less predictive in pts who did not meet trial criteria Ryan J Tedford MD Mandeep R. Mehra, MBBS, MSc, FRCP (London) Farooq Sheikh Jagpreet Grewal Alexander Hajduczok, MD 🇺🇦🙏

🔗 jhltonline.org/article/S1053-…

Letter to the Editor regarding this outstanding work in developing a predictor tool for pulmonary hypertension in patients with IPF and a call for collaboration efforts.

🔗 jhltonline.org/article/S1053-…

Based on SRTR data, Belga et al. found a 27% higher hazard of death among CMV D+/R- lung transplant recipients, compared to CMV D-/R-, with evidence of disproportionate mortality among older (≥60) recipients. Sara Belga, MD MPH

🔗 jhltonline.org/article/S1053-…

The Michigan Bleeding Risk model: A new risk assessment tool to predict gastrointestinal bleeding in HeartMate 3 left ventricular assist device recipients, based on pre-implant characteristics. Yoav Hammer

🔗 jhltonline.org/article/S1053-…

Shock belongs The ISHLT! #CSWG team has arrived! Check out the ISHLT 2023 shock guideline documents; substantial grant funding available Thomas Hanff, MD MSCE. JHLT Manreet Kanwar Ulrich Jorde Khue Ton Jaime Hernandez-Montfort Maryjane Farr MD MSc, FACC FAST FHFSA FAHA Anthony Carnicelli, MD FACC Navin Kapur

Check it out! We loved doing this work and continue to do so. Many insights to be gained from PVL and correlation with clinical variables to try and bring to the broader LVAD patient community

Pressure-volume loops uncover occult RV dysfunction & ↓ reserve in LVAD, w/ PAPi as potential surrogate; ↓septal contraction 2/2 LV unloading a possible mechanism based on echo septal strain Paul Scheel, Steve Hsu, Johns Hopkins Cardiology

🔗 jhltonline.org/article/S1053-…

Kiran Khush stealing the show with the first report from CareDx® SHORE registry! Dual + GEP/cfDNA with the highest incidence of rejection and more predictive of future events than biopsies!
The ISHLT JHLT #ishlt2024 Shout out to all of our co-investigators!