A validation strategy to assess the role of phase separation as a determinant of macromolecular localization: cell.com/molecular-cell…

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Splice modulators target PMS1 to reduce somatic expansion of the Huntington’s disease-associated CAG repeat: nature.com/articles/s4146…

A prion-like protein regulates the 2-dimensional to 3-dimensional growth transition in the moss Physcomitrium patens biorxiv.org/content/10.110…

RAB32 Ser71Arg in autosomal dominant Parkinson's disease: linkage, association, and functional analyses - The Lancet Neurology thelancet.com/journals/laneu…

Evolution of T cells in the cancer-resistant naked mole-rat: nature.com/articles/s4146…

Visualizing chaperone-mediated multistep assembly of the human 20S proteasome: nature.com/articles/s4159…

Problem choice and decision trees in science and engineering: Cell cell.com/cell/fulltext/…

Kinetic trapping organizes actin filaments within liquid-like protein droplets: nature.com/articles/s4146…

An adaptive biomolecular condensation response is conserved across environmentally divergent species: nature.com/articles/s4146…

Our multi-omics study reveals extensive and surprising cellular adaptations to proteasome hyperactivation in C. elegans, with therapeutic potential for neurodegenerative diseases. biorxiv.org/content/10.110…

RANBP17 Overexpression Restores Nucleocytoplasmic Transport and Ameliorates Neurodevelopment in Induced DYT1 Dystonia Motor Neurons jneurosci.org/content/44/15/…

DNA G-Quadruplex Is a Transcriptional Control Device That Regulates Memory jneurosci.org/content/44/15/…

Impairment of the glial phagolysosomal system drives prion-like propagation in a Drosophila model of Huntington's disease, exciting work by Maggie Panning Pearce et al.: jneurosci.org/content/early/…

mRNA drug offers hope for treating a devastating childhood disease nature.com/articles/d4158…

How to supercharge cancer-fighting cells: give them stem cell skills nature.com/articles/d4158…

Proteasome hyperactivation rewires the proteome enhancing stress resistance, proteostasis, lipid metabolism and ERAD in C. elegans biorxiv.org/content/10.110…

An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains: cell.com/molecular-cell…