Gas and propane stoves can boost long-term nitrogen dioxide exposure to concentrations well above the World Health Organization’s guidelines, suggests a new air contamination model. scim.ag/6Q9

The link between fetal (in utero) and childhood exposure to tobacco smoke, and metrics of accelerated biological aging science.org/doi/10.1126/sc…
Science Advances across the range of polygenic risk scores for aging

New research quantifies the extent to which early-life exposure to tobacco biologically ages and predisposes people to conditions including cardiac disease, type 2 diabetes, and more. scim.ag/6PH

Happy to share the conformational ensemble of wild-type human TRPV3. For the first time the channel structure is open by applying agonists, 2-APB or THCV, without sensitizing mutations! Kirill Nadezhdin Arthur Neuberger Ira Talyzina science.org/doi/10.1126/sc…

Researchers present a 32-question checklist for conducting #MachineLearning -based scientific research.

Machine learning methods are widespread across scientific disciplines, and this checklist is a step toward increasing standardization for use. scim.ag/6OS

New paper out in Science Advances! Here our very talented former postdoc Bar establishes a link between diffuse upper plate seismicity and long-term deformation encoded in subduction landscapes. Congrats, Bar! science.org/doi/10.1126/sc… Luca C Malatesta Boris Gailleton Dr. Lucile Bruhat

Excited to share that our paper introducing the REFORMS checklist is now out Science Advances!

In it, we:
- review common errors in ML for science
- create a checklist of 32 items applicable across disciplines
- provide in-depth guidelines for each item

science.org/doi/10.1126/sc…

A new peptide-carrying magnetic nanoparticle has resolved both biological and behavioral symptoms in mouse models of #AlzheimersDisease . scim.ag/6OA

Extreme floods in Pakistan lead to severe heatwaves in China due to Asian summer monsoon variability—and seemingly occur independently of El Niño forcing. scim.ag/6N9

Higher temperatures typically mean greater rainfall, but climate models show the trend reverses above 320 K, a phenomenon with significant implications for extreme hothouse climates. scim.ag/6MJ

#Neuron activity in mouse motor cortexes can be partitioned into multiple subspaces with different dynamics.

This multidimensionality allows the brain to perform multiple functions at the same time. scim.ag/6M7

Higher doses of drugs known to yield toxic effects on the liver do the most damage to liver cells when one circadian clock gene is at peak activity, suggests a new in vitro study. scim.ag/6LB

A new study demonstrates how a diversity of functional plant traits can help imperiled Canadian drylands endure drought and #ClimateChange . scim.ag/6Lf

A 3D-printed, bioactive #hydrogel promotes rats’ recovery from injuries to the muscle-tendon junction, a promising treatment option for common strain injuries. scim.ag/6KR

Myriad microbial natural products—some of which may have pharmaceutical potential—have been discovered in hydrocarbon-rich deep sea fissures. scim.ag/6Kq

Excited to share our released manuscript in Science Advances. We show that #PlasticPollution is tightly linked to #PlasticProduction , there is literally a 1 to 1 relationship between them! Plastic production reduction is key, especially for single use.
science.org/doi/10.1126/sc…

Excited to share our latest paper revealing ancient matrilineal haplotypes linked to sex-specific plumage differences in two cuckoos, predating speciation! Out today in Science Advances

science.org/doi/10.1126/sc…

Short thread on what we found... 🧵 1/8

Research involving global audits of plastic pollution from 2018 to 2022 has revealed that 52% of the nearly 2 million inventoried items had no discernible branding and could not be traced back to producers. scim.ag/6Jx

In new experiments, the psychoactive drug MDMA induced empathy-like behaviors in mice, partially relieved social deficits in a mouse model of autism, and even enhanced the social transfer of pain between animals. scim.ag/6Jf