Looking forward to this endevour!

This one was a labor of (hard work and) love. I’m quite proud of how it turned out! This was a team effort in the best sense of the word and a wonderful process beginning to end. science.org/doi/10.1126/sc…

Valid germline gene sets offer opportunities for improved analysis of #antibody and #TCR repertoires. We present a forward-looking data model for naming alleles and building robust germline sets for such purposes. #AIRRseq sciencedirect.com/science/articl… airr_community

Today the funding starts for #Base4NFDI, @NFDI4Agri, NFDI4BIOIMAGE, NFDI4Energy, NFDI4Immuno - @[email protected], NFDI 4Memory (@[email protected]), NFDI4Objects and NFDIxCS. We warmly welcome you to our #NFDI network! #FDM #RDM #FAIRdata

Targeting MCAM for next-generation modulation of leucocyte trafficking academic.oup.com/brain/advance-…

A new episode of #OnAIRR - the podcast of the AIRR Community is available. Prof Xenophon Papademetris, Yale Department of Radiology & Biomedical Imaging, USA, introduces Software as a Medical Device. Subscribe and listen in your favourite app or grab the episode here: onairr.airr-community.org

A new episode of #OnAIRR - the podcast of the AIRR Community is available. We discuss AIRR-seq, machine learning and disease diagnostics with Maxim Zaslavsky, Scott_Boyd_Lab_Stanford. Subscribe and listen in your favourite app or grab the episode here: onairr.airr-community.org

Also included is an exciting session devoted to identify the obstacles in turning AIRR-seq into a diagnostic tool

At this year’s ECTRIMS in Milano with the team #MSMilan2023

Beautiful example of bedside -> bench -> bedside #Tcell immunology for the treatment of #autoimmunity nature.com/articles/s4159…

I wrote a review in Science Translational Medicine with my long-time collaborator Heinz Wiendl about what we can learn about CNS immunity when we look closely at patients treated with interventions that target BBB trafficking. science.org/doi/10.1126/sc…

The new special issue of #ScienceTranslationalMedicine is out! This issue features a collection of studies and articles exploring frontiers in #neuroimmunology and the role of the immune system in neurological conditions such as Parkinson's disease. scim.ag/4KN

Our #OpenAccess paper on human CNS #macrophages went online today. It was a multi-year collaborative effort between clinician scientists from #Neuropathology #Neurosurgery #Oncology and #gynacology. It struck with the question: what are the phenotypes of human CNS macrophages? /1

I wrote a commentary about a new MS CSF scRNAseq study that was recently published in Brain Transcriptomics reveals CSF cellular composition in multiple sclerosis but detects no viral RNA academic.oup.com/brain/article/…

Transcriptomics reveals CSF cellular composition in multiple sclerosis but detects no viral RNA New scientific commentary by Nicholas Schwab tinyurl.com/nmw5dej8

AIRR Community Meeting VII – Learnings and Perspectives: antibodysociety.org/the-airr-commu…

Glad to finally be able to showcase our #TCR-#epitope annotation tool DETECT and the cool results we have gotten with it at the airr_community #AIRRC7 conference! And as of now you can use it yourself!

Rare diseases need some attention, too. Chemokine-mediated cell migration into the central nervous system in progressive multifocal leukoencephalopathy: Cell Reports Medicine cell.com/cell-reports-m…

Structure-based prediction of T cell receptor recognition of unseen epitopes using TCRen. Yes, it works: pubmed.ncbi.nlm.nih.gov/38987378/

The next chapter in our continued effort to understand EBV and MS: Broader anti-EBV TCR repertoire in multiple sclerosis: disease specificity and treatment modulation academic.oup.com/brain/article/…