SCI leader Crystal Mackall & others identify #macrophages as major regulators of T-cell persistence & illustrate the fundamental challenge of combining T-cell-directed therapeutics with those designed to activate macrophages. go.nature.com/4apN0L6 #CARTcells #CD47
Mackall Lab

SCI members Nam Bui, MD, Kristen Ganjoo, MD & others found a pattern of better overall survival for males across histologic and molecular subgroups of #SoftTissueSarcoma . bit.ly/3K7QXta Nam Bui Kristen Ganjoo

Congratulatiosn to SCI leader Melissa Bondy, who received the American Society of Preventive Oncology (ASPO) Joseph F. Fraumeni, Jr. Distinguished Achievement Award, recognizing her excellence in preventive oncology, cancer control, and prevention. bit.ly/3wKBFaN

I'm inspired by the collaborative efforts and insights shared at our Curing Advanced Cancer Think Tank. I am immensely thankful for everyone's dedication as we work tirelessly toward a cure. Together, we will tackle #AdvancedCancer . stan.md/4aoPAB3 #CancerResearch

We mourn the loss of Janice 'Wes' Brown with great sadness. Wes dedicated her life to pioneering stem-cell therapies, offering hope to immunocompromised patients. May we cherish her spirit as we reflect on her enduring legacy. stan.md/3UyNngJ Stanford BMT & Cell Therapy

Stanford and U Penn researchers found no link between #CARTcells therapies and the development of secondary T-cell malignancies. bit.ly/3wuNxh5 Parker Institute for Cancer Immunotherapy #CellTherapy

Congratulations again on this fantastic milestone! Stanford BMT & Cell Therapy

Congratulations to SCI Deputy Director Heather Wakelee on receiving the ECOG-ACRIN Cancer Research Group Remarkable Mentor to  #WomenInOncology  Award. Well deserved! Heather Wakelee  #EAOnc

SCI members Michael Sargent Binkley, Richard Hoppe & others develop the lymphocyte-predominant international prognostic score to identify high-risk patients & inform upcoming prospective clinical trials for patients with low scores. bit.ly/4bjNSSA #HodgkinLymphoma

SCI member James Brooks & others found AZGP1 is a negative regulator of angiogenesis, such that loss of AZGP1 promotes angiogenesis in #ProstateCancer . bit.ly/3JImWQF

SCI member Julien Sage & others found that cell cycle arrest can enhance sensitivity to ferroptosis induced by covalent GPX4 inhibitors but not system xc− inhibitors. bit.ly/44jZuTb Julien Sage @SJD95

I encourage you to apply for the SCI-JEDI Pilot Seed Grant. The grant supports projects that make progress toward inclusive excellence at the Stanford Cancer Institute.stan.md/49P8IrS #CancerHealthEquity

SCI member Joel W. Neal, MD, PhD & others found no significant improvement in overall survival with atezolizumab +cabozantinib vs docetaxel after checkpoint inhibitor treatment and chemotherapy in patients with metastatic #NonSmallCellLungCancer ( #NSCLC ). bit.ly/3w7DvSO

Congratulations to Stanford Cancer Biology Crabs Sharon Lo, and James Occean for receiving Paul & Daisy Soros Fellowships. stanford.io/4b5UwM1 PD Soros Fellowships Stanford Cancer Biology PhD Program #GoCrabs !

SCI member Eleni Linos & others clinicians benefit from AI assistance in #SkinCancer diagnosis regardless of their experience level. bit.ly/3xJk6bk #AIhealthCare Eleni Linos

SCI members & others show how #GenomeEngineering using #Cas9 & AAV repair templates form concatemeric insertions of viral vectors & outline mitigation strategies. go.nature.com/3Q8vq7f Majeti Lab

SCI members @adamdelazerd, Yonatan Winetraub, Kavita Sarin, & others developed a noninvasive #VirtualBiopsy using micro-registered optical coherence tomography. bit.ly/3xA0JSb

SCI leader Mackall Lab & others found that a protein called #FOXO1 improves the survival and function of CAR T cells, which may lead to more effective #CARTcell therapies &could potentially expand its use in difficult-to-treat cancers. go.nature.com/43UJBCs #CellTherapy

I encourage you to apply for the SCI Equity Impact Research Grants. Together, let's reduce #CancerDisparities . Proposals are due May 1st. stan.md/3Ubr1mj #CancerHealthEquity

Congratulations to Stanford Cancer Institute faculty members Laura Attardi Laura Attardi, Nathanael Gray, and Roel Nusse for their induction as Fellows of the American Association for Cancer Research AACR at the AACR Annual Meeting in San Diego. #Chemistry #p53 #WNT