Age-Dependent RGS5 Loss in Pericytes Induces Cardiac Dysfunction and Fibrosis | Circulation Research ahajournals.org/doi/full/10.11…

Molecular mechanisms of aging and anti-aging strategies biosignaling.biomedcentral.com/articles/10.11…

Check out Farsh’s preprint! He found a new role for SHP-1: allowing neutrophils to enter inflamed lungs without causing bleeding, pointing to potential new ways to suppress harmful neutrophil responses: Farshid

Now with link: I will have two postdoc positions and a technical post in my new(ish) lab in UCL. One biased to wet experiments with chemoattractant gradients, and one more based on modelling and maths. But both posts encompassing both. Drop me a line! ucl.ac.uk/work-at-ucl/se…

The phrase ‘metastasis accounts for 90% of cancer deaths’ is one of the most widely used in cancer research, yet it is overly simplistic & imprecise. Here we dig deeper into the events leading to cancer mortality nature.com/articles/s4156… 1/2

Prizes for best talk for Clare Latta and best poster for Loïc Rolas at our William Harvey Research Institute Annual Res Day, very proud!

Happy to share our paper on impact of senescent ECs on neutrophil trafficking, brilliantly led by Loïc Rolas and Monja Stein . Thanks to our funders Wellcome British Heart Foundation and all collaborators 👉link: shorturl.at/JZyDu

Dr. Loïc Rolas and the Sussan Nourshargh Lab at Queen Mary University of London applied confocal intravital 🔬 microscopy to 🌡️ inflamed tissues of an endothelial cell (EC)-specific progeroid mouse model, characterized by profound indicators of EC senescence. EMBO Reports | bit.ly/4cICu3r

Older and Leakier: Homing in on inflamed tissues in live mice by high-res #microscopy reveals #inflammation is promoted by #senescent endothelial #cells. Image & research by Loïc Rolas & Monja Stein et al @Noursharghlab William Harvey Research Institute in EMBO Reports. On bpod.org.uk/archive/2024/7…

Great session on #neutrophil endothelial cell interaction at IVBM 2024 sponsored by CRC TRR332. Thanks to Sussan Nourshargh Lab Daniela Maier-Begandt and Markus Sperandio for great talks.

The choroid plexus synergizes with immune cells during neuroinflammation Cell cell.com/cell/fulltext/…

Neutrophil Extracellular Traps (NETs) capture microbes. But who would have thought that #neutrophils can become trapped themselves? Check out our study MPI of Immunobiology & Epigenetics and Universität Münster on Mast Cell Intracellular Traps (MITs) at Cell ….

#WeekendRead! #ImmuneCannibalism! Wellcome #nexocytosis Cell Tim Lämmermann Lab, Mihlan &co! In #allergy, mast cells attract, eat, & kill neutrophils, steal their effectors & DNA that can be released afterwards to induce type I #interferons via cGAS dlvr.it/TBRsZ7

Please, RT If you love #macrophages #neutrophils #dendriticcells don't miss #phagocyte2025 📆26-28 March 2025 📍CNIC Madrid 🌍top speakers phagocytes2025.com/index.php/spea… 🔬Submit your latest research for oral presentation or poster phagocytes2025.com/index.php/abst…

Apply by 9 September for a funded early-career place at our 'Immune Cell Interactions in Development, Homeostasis and Immunity' Workshop, organised by Bousso Lab Griffiths Lab Sarris Lab & Michael Sixt biologists.com/workshops/febr… J Cell Science

September issue is live! embopress.org/toc/14693178/2… The cover features work by Loïc Rolas, Monja Stein Sussan Nourshargh Loïc Rolas @Noursharghlab William Harvey Research Institute and coworkers showing that senescent endothelial cells promote pathogenic neutrophil infiltration. embopress.org/doi/full/10.10…

#NeutrophilPower! #FriendsOrFoes?! 💥 Excited 💥 to share our new work Cancer Immunology Research AACR on the good & bad that neutrophils do during #colorectal #cancer development! Many congrats to Sreya Ghosh for spearheading this! #gut #IBD Cancer Research Institute #STAR doi.org/10.1158/2326-6…

Check our new #STARProtocol on #Endothelial cell CLXEM! Thanks Azumi Yoshimura Lucy Collinson Sussan Nourshargh Lab Lorena Pérez Beccy Saleeb

Beatiful neutrophil art #Neutrophil2024