Michael Totty
@mictott
Postdoctoral researcher at @JohnsHopkinsSPH ; Neuroscientist ; Computational Biology. Person who stutters; Opinions are my own
ID: 72455359
https://mictott.github.io/ 08-09-2009 02:57:48
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The first piece of my PhD work is out in Neuropsychopharmacology! We explored the effects of infralimbic stimulation and protein synthesis inhibition during fear memory consolidation🧵 Steve Maren 🐀🧠💭😨 James Hassell Vitor Juliano et al. nature.com/articles/s4138…
Bringing my account back to life just in time for #FluorescenceFriday with a peek at our preliminary dive into the human LC🔵in AD. Glials & microvessels surrounding tangles - let the adventure begin into their -omics! Major credit to Heena Divecha for the perfect slice!
Just dropped- a really epic work from Dr. Julia C Lemos and Larry Zweiffel, finally uncovering the functions of the enigmatic nucleus-accumbens CRH cells in reward behaviors. Unsurprisingly, this peptide's actions remain, ahem, WEIRD. sciencedirect.com/science/articl…
Exciting new paper exploring the intersection of aging and psychopathology. In Nature Neuroscience out of Binder Lab by Anna, focusing on the orbitofrontal cortex from NSW Brain Tissue Resource Centre 🇦🇺, an interesting but understudied area in the human brain nature.com/articles/s4159…
What happens when you use picrotoxin to stimulate the infralimbic cortex in🐀after fear conditioning?😱 Find out in this recent Neuropsychopharmacology paper from Hugo Bayer, Steve Maren 🐀🧠💭😨, & colleagues ⬇️ nature.com/articles/s4138…
New in Nature Neuroscience, we present DPAD, a deep learning method for dynamical modeling of neural-behavioral data & dissociating behaviorally relevant dynamics. It enables diverse neurotech & neuroscience use-cases. 👏Omid Sani 💻github.com/ShanechiLab/DP… 📜nature.com/articles/s4159… 🧵⬇️
#SpatialTranscriptomics Bin2cell reconstructs cells from high resolution #VisiumHD data 10x Genomics Transforming #VisiumHD 2-μm matrix into Single-Cell Spatial data StarDist segmentation (H&E Nuclei detection + expansion + fluorescence model-based salvage secondary