Urine Epidermal Growth Factor and Kidney Function Decline in Middle-Aged Adults

Higher urine EGF concentrations are associated with slower eGFR decline; other kidney tubule biomarkers may lack a consistent association with kidney function decline

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CKD Stage and Cardiovascular and Mortality Events Among Older Adults: The SPRINT Trial

In this cohort, low eGFR and low albuminuria among older SPRINT participants, was associated with higher mortality, but not with cardiovascular events.

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Anti-Brush Border Antibody Disease: A Case Series

Authors report 9 patients presenting with acute kidney injury, highlighting the poor prognosis of ABBA disease & potential benefit with anti B cell therapy or treatment of the underlying malignancy.

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EDITORIAL
APOL1 High-Risk Genotypes and Kidney Disease Risk in Middle-Aged Black Adults: More Questions Than Answers

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Atomoxetine for Intradialytic Hypotension in a Patient on Hemodialysis: A Case Report

Authors reports a case of low-dose atomoxetine alleviating symptoms & blood pressure in a patient with severe intradialytic hypotension during hemodialysis

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SGLT2 Inhibitor Use for Treatment of Hypocitraturia in a Distal Renal Tubular Acidosis

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IMAGES IN KIDNEY MEDICINE
Dialysis Patient With a Unique Rash

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Acute Kidney Injury in Inflammatory Bowel Disease Patients: A Nationwide Comparative Analysis

Researchers report that the prevalence & risk of AKI among hospitalization with IBD is greater than that of the hospitalization in the general population.

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Volume and Body Composition in Hemodialysis Patients: A Bioimpedance Study Assessing Differences by Sex

Authors report sex differences in pre-dialysis fluid status & a need to re-analyze datasets for bioimpedance-derived measures of body composition

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Kidney Medicine has consistently published high quality, patient-oriented research Dan Weiner

Great to have Mahboob Rahman now at the helm

National Kidney Foundation Journal Names New Editor-in-Chief | National Kidney Foundation
⁦Mahboob Rahman⁩ kidney.org/news/national-…

Remdesivir and Kidney and Cardiovascular Outcomes in COVID-19 Patients With Reduced GFR

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Urine Biomarkers of Kidney Tubule Health and Risk of Incident CKD in Persons Without Diabetes: The ARIC, MESA, and REGARDS Studies

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Informed Dialysis Modality Selection Among Veterans With Advanced CKD: A Community-Level Needs Assessment

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Sparsentan for Focal Segmental Glomerulosclerosis in the DUET Open Label Extension: Long-Term Efficacy and Safety

In this paper, investigators report that patients taking sparsentan had sustained proteinuria reduction & no unexpected adverse effects

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Pro-Neurotensin/Neuromedin N and Risk of Incident Chronic Kidney Disease and Other Kidney Outcomes in Community-Living Individuals: The REGARDS Study

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Cystatin C Use for CKD Detection in the Veterans Health Administration System: A Qualitative Study of Barriers and Facilitators

Authors report that the use of cystatin C is limited due to lack of awareness, a knowledge gap, training & workflow challenges

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Hemodiafiltration versus Hemodialysis in End-Stage Kidney Disease: A Systematic Review and Meta-analysis

Authors demonstrated that patients receiving HDF experienced a reduction in all-cause mortality, CV mortality & infections-related mortality.

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A Review of Focal Segmental Glomerulosclerosis Classification With a Focus on Genetic Associations

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APOL1 Kidney Risk Variants & Long-Term Kidney Function in Healthy Middle-Aged Black Individuals:The Atherosclerosis Risk in Communities (ARIC)Study

Authors conclude that APOL1 genotype does not appear to be a major driver of future risk of kidney disease

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