Radiation-primed TGF-β trapping by engineered extracellular vesicles for targeted glioblastoma therapy.
| Tian Tian & coworkers, Nanjing Medical Univ. |
[50 days' free access]
#radiation #ExtracellularVesicle #glioblastoma
doi.org/10.1016/j.jcon…

Small extracellular vesicle-mediated CRISPR-Cas9 RNP delivery for cardiac-specific genome editing.
| Boyoung Joung & coworkers Yonsei University |
[50 days' free access]
#GenomeEditing #CardiacSpecific #ExtracellularVesicle
authors.elsevier.com/a/1j6OkcI2-5wq7

Prostate cancer-derived extracellular vesicles metabolic biomarkers: Emerging roles for diagnosis and prognosis.
| Yong Li UNSW Medicine & Health | Drug Delivery Australia
#ExtracellularVesicle #biomarker #diagnosis
doi.org/10.1016/j.jcon…

Thermosensitive gel-nano system against esophageal cancer via restoring p53 activity and boosting T-cell immunity.
| Yourong Duan Shanghai Jiao Tong University |
#thermosensitive #gel #Tcell
doi.org/10.1016/j.jcon…

Hypotonic, gel-forming delivery system for vaginal drug administration.
| Laura M. Ensign Johns Hopkins ChemBE | CRS Focus Group - Skin and Mucosal Delivery
#VaginalDelivery #GelForming
doi.org/10.1016/j.jcon…

Phospholipids of inhaled liposomes determine the in vivo fate and therapeutic effects of salvianolic acid B on idiopathic pulmonary fibrosis.
| Zipeng Gong, Guizhou Medical Univ. |
#liposome #inhalation #phospholipid #fibrosis
doi.org/10.1016/j.jcon…

Photothermal-controlled NO-releasing Nanogels reverse epithelial-mesenchymal transition and restore immune surveillance against cancer metastasis.
| Yinan Zhong, China Pharmaceutical Univ. |
#nanogel #NitricOxide #photothermal
doi.org/10.1016/j.jcon…

Softening the tumor matrix through cholesterol depletion breaks the physical barrier for enhanced antitumor therapy.
| Meiying Wu 中山大学(SYSU) |
#TumorMatrix #cholesterol #PhysicalBarrier
doi.org/10.1016/j.jcon…

Lipid conjugate dissociation analysis improves the in vivo understanding of lipid-based nanomedicine.
| Alexander Kros Universiteit Leiden | CRS BeNeLux & France Local Chapter
#LipidConjugate #nanomedicine #dissociation #liposome
doi.org/10.1016/j.jcon…

In situ gelling systems for ocular drug delivery.
| Indu Pal Kaur Panjab University, Chandigarh | CRS Indian Chapter
#OcularDelivery #InSitu #gel #polymer
doi.org/10.1016/j.jcon…

Hollow microneedles for ocular drug delivery.
| Raghu Raj Singh Thakur QUB Pharmacy School | UKICRS
#microneedle #ocular #suprachoroidal
doi.org/10.1016/j.jcon…

An informative and inspiring article J Controlled Release by Jindrich (Henry) Kopecek Molecular Pharmaceutics - University of Utah UtahBME summarizing his life time work from basic hydrogel studies in the 1960s to Drug Free Macromolecular Therapeutics in the present ..and still going. A true pioneer and pioneering work.

Lipid nanoparticle-based strategies for extrahepatic delivery of nucleic acid therapies – challenges and opportunities.
| Jens B. Simonsen, Jbsimonsen Consult |
[50 days' free access]
#extrahepatic #LipidNanoparticle #NucleicAcid
authors.elsevier.com/a/1j6LicI2-5wg6

Spleen-targeted delivery systems and strategies for spleen-related diseases.
| Jian You Zhejiang University |
[50 days' free access]
#SpleenTargeting #DrugDelivery
authors.elsevier.com/a/1j6LicI2-5wnc

Microenvironment Responsive Hydrogel Exerting Inhibition of Cascade Immune Activation and Elimination of Synovial Fibroblasts for Rheumatoid Arthritis Therapy.
| Liang Ge, China Pharmaceutical Univ. |
[50 days' free access]
#pHsensitive #hydrogel
authors.elsevier.com/a/1j65LcI2-5wpZ

Image-based predictive modelling frameworks for personalised drug delivery in cancer therapy.
| Wenbo Zhan University of Aberdeen | UKICRS
[50 days' free access]
#ArtificialIntelligence #imaging #modelling
authors.elsevier.com/sd/article/S01…

Current status and advances to improving drug delivery in diffuse intrinsic pontine glioma.
| Susan Hua Newcastle Pharmacy |
#BrainDelivery #BloodBrainBarrier #glioma
doi.org/10.1016/j.jcon…

Intracellular Criegee's mechanism-based synergistic ozone therapy mediated by oleogels for cancer treatment.
| Lingyun Zhao Tsinghua University |
#oleogel #OzoneTherapy
doi.org/10.1016/j.jcon…

Hydrophilic biomaterials: From crosslinked and self-assembled hydrogels to polymer-drug conjugates and drug-free macromolecular therapeutics.
| Jindřich Kopeček UtahBME |
[50 days' free access]
#hydrogel #SelfAssembly #copolymer #DrugConjugate
authors.elsevier.com/a/1j6DicI2-5woN

“Click” amphotericin B in prodrug nanoformulations for enhanced systemic fungemia treatment.
| Juntao Luo Upstate Medical University |
[50 days' free access]
#prodrug #dendrimer #ClickChemistry
authors.elsevier.com/a/1j5bfcI2-5wmy