Study contributes novel evidence highlighting value of leveraging genetic information across multiple psychopathological traits that correlate with major depression. Diverse data essential for future generalizability. ja.ma/4bkGsPj Poppy Grimes Alex Kwong

The contribution of mental illness to the escalating rate of maternal mortality is not well recognized. Expanding the conceptualization of healthcare to address social and systemic determinants holds promise to impact the health of our pregnant population. ja.ma/4bk8NVG

Findings suggest that RNA damage from oxidation may be a mechanism in the accelerated aging observed in psychiatric illness and could have utility as a marker of mortality risk in these common disorders. ja.ma/4b3ilVd

Most viewed in the last 7 days from JAMA Psychiatry:

Do prospective and retrospective measures of childhood maltreatment show different associations with psychopathology?

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A nationwide study finds an extremely high immediate suicide risk among discharged patients hospitalized for depression. The study finds several risk factors for risk of suicide within days & temporal patterns in the relative effects of factors over time. ja.ma/4bdGvg1

Viewpoint discusses the current state of mental health parity reform, proposed amendments, and the challenges and considerations in play. ja.ma/4arHacx

Risk for depressive symptoms in adolescence may begin during pregnancy and in a sex-dependent manner. Higher levels of inflammation are linked to internalizing and externalizing symptoms in childhood, and later depressive symptoms in adolescence. ja.ma/3QshMfh

Most viewed in the last 7 days from JAMA Psychiatry:

Do prospective and retrospective measures of childhood maltreatment show different associations with psychopathology?

ja.ma/4byQxry

More than 320,000 children in the US lost a parent to drug overdose between 2011-2021, with significant disparities evident across racial and ethnic groups. ja.ma/4ajT48g

In a diverse sample of 5930 post-menopausal women followed for 6 years, those with higher optimism had healthier physical functioning at older ages as well as slower rates of decline in their functioning during follow-up. ja.ma/4aWr4bT

This JAMA Insights article reviews Americans with Disabilities Act (ADA) rules for patients, visitors, and other members of the public bringing service animals into health care settings. ja.ma/4bNYrOb

Most viewed in the last 7 days from JAMA Psychiatry:

What are characteristics of adolescents with a history of depression who do not endorse risk via the Patient Health Questionnaire item 9 before self-harm or suicide?

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Results of this study suggest that persistent shorter sleep duration across childhood was associated w/ higher risk of developing psychosis in young adulthood. Inflammation as measured by IL-6 level could be one of the potential mechanistic pathways. ja.ma/4ahr3Oh

In this cohort study of publicly and commercially insured pregnant individuals in the US, amphetamine/dextroamphetamine and methylphenidate exposure during pregnancy did not meaningfully increase the risk of childhood neurodevelopmental disorders. ja.ma/4aWr4sp

A collaborative care intervention did not influence QOL, depressive & anxiety symptoms, or physical function of older adults w/ injury at 12 mos. It may improve the psychological health of patients w/ symptoms of anxiety or depression at time of admission. ja.ma/4ah1D3s

Controlling for genetic and environmental confounding, study revealed 21-41% of mental health conditions in Australia are attributable to child maltreatment. Over 1.8 million cases & 184,000 DALYs could be prevented if child maltreatment was eliminated. ja.ma/4brnohT

Cognitive function in psychosis & schizophrenia patients is impaired already at illness onset. However meta-analytic evidence shows significantly more variability in patients than controls, calling for personalized assessment, treatment & rehabilitation ja.ma/4dox2Uk

Longitudinal Associations Between Optimism and Objective Measures of Physical Functioning in Women, from JAMA Psychiatry, free to read online during #APAAM24
(Link to microsite) ja.ma/3UHByG5

Final day of exhibits at #APAAM24 . Visit us at booth 1328 to learn more JAMA_current, JAMA Psychiatry and our other Network journals, and get recent #psychiatry research articles for your trip home

Three genetically distinct and longitudinally stable subgroups display brain changes reflecting differential susceptibility to Alzheimer Disease and other neurodegenerative diseases, cognitive decline, and clinical progression. ja.ma/4aY81Ok